Active B12


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A vitamin B12 level test checks the amount of vitamin B12 in the body. Normal levels usually range from 200 to 900 picograms per milliliter, but the way of measuring will depend on the laboratory.

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Purpose of the test

The primary objective of testing for Total B12 and Active B12 is to determine the levels of vitamin B12 present in the body. Total B12 measures both the active and inactive forms of the vitamin, while Active B12 specifically measures the form that the body can use.

Who Should Get Tested

Individuals who exhibit symptoms associated with a vitamin B12 deficiency, such as fatigue, anemia, neurological features, or sore tongue, should consider getting tested. Additionally, those concerned about thyroid disorders or experiencing unexplained fatigue might benefit from this test.

Blood Test Preparation Guidelines
Time of day
It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
Drinking water prior to testing can help with sample collection.
Other factors
Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Total B12 measures both active and inactive forms of the vitamin. However, only Active B12 is available for use by the body's cells. Typically, Active B12 makes up 10% - 30% of all the B12 in the body. A test that only measures Total B12 might show normal levels, but the individual could still have low levels of Active B12. Thus, testing specifically for Active B12 provides a more accurate picture of the body's B12 status. Symptoms of vitamin B12 deficiency can range from fatigue and anemia to neurological issues and bone marrow suppression. If levels are found to be deficient, dietary adjustments or supplements might be recommended.

AI-Powered Insights and Expert Validation
Advanced AI Interpretation
Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.
Expert Doctor Confirmation
While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.
Language Model and Trusted Sources
At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.
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