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Alpha-1-Antitrypsin

Alpha-1-Antitrypsin

Alpha-1-Antitrypsin (AAT) testing is an essential diagnostic procedure used to detect AAT deficiency, a genetic disorder that can lead to severe lung and liver diseases. The test measures AAT protein levels in the blood, identifying individuals with Alpha-1 Antitrypsin Deficiency (AATD). This condition can cause chronic obstructive pulmonary disease (COPD), emphysema, and liver cirrhosis. Early diagnosis through AAT testing is crucial for timely intervention, potentially slowing or preventing disease progression. The test involves a simple blood draw, with minimal preparation required. While generally safe, minor risks such as bruising or infection exist. Family testing is recommended, as AATD is inherited, allowing carriers to make informed health decisions. At-home testing options, like fingerstick blood samples or cheek swabs, offer convenience. Genetic counseling is advised to understand the implications of testing. Overall, AAT testing is vital for managing and preventing complications associated with AATD.

Price of test:£107

The lowest price from the last 30 days: £107

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

Alpha-1-Antitrypsin (AAT) testing is essential for diagnosing Alpha-1 Antitrypsin Deficiency (AATD), a genetic disorder affecting the lungs and liver. The test measures AAT protein levels in the blood, identifying deficiencies that can lead to conditions like COPD, emphysema, and liver cirrhosis. Key points include:

- Purpose: Diagnose AATD for early intervention.
- Procedure: Simple blood draw with minimal risks.
- Results: Low AAT levels indicate deficiency.
- Importance: Early detection prevents severe complications.
- Family Testing: Essential for identifying carriers.

Who Should Get Tested

AAT testing is essential for diagnosing Alpha-1 Antitrypsin Deficiency (AATD), a genetic disorder affecting the lungs and liver. This test measures AAT protein levels in the blood, identifying deficiencies that can lead to severe health issues. Key points include:

- Purpose: Diagnose AATD to prevent lung and liver damage.
- Procedure: Simple blood draw with minimal risks.
- Results: Low AAT levels indicate potential health risks like COPD and liver cirrhosis.
- Family Testing: Important for identifying carriers among relatives.
- Early Detection: Crucial for timely intervention and lifestyle adjustments.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for Alpha-1-Antitrypsin (AAT) testing is crucial for managing health outcomes. This test measures AAT protein levels in the blood to diagnose Alpha-1 Antitrypsin Deficiency (AATD), a genetic disorder. Normal AAT levels range from 80 to 200 mg/dL. Abnormal results indicate lower levels, suggesting AATD, which can lead to:

- Chronic Obstructive Pulmonary Disease (COPD)
- Emphysema
- Liver Cirrhosis

Early detection allows for timely intervention, reducing the risk of severe lung and liver diseases. Family testing is recommended to identify carriers.

Price of test:£107

The lowest price from the last 30 days: £107

AI-Powered Insights and Expert Validation

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