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Alpha Foetoprotein

Alpha Foetoprotein

The Alpha-fetoprotein (AFP) test is a vital diagnostic tool used in both prenatal care and oncology. AFP, a protein produced by the fetal liver, is present in amniotic fluid and crosses into the mother's bloodstream. During pregnancy, the AFP test is part of multiple marker screenings to assess the risk of birth defects and genetic disorders, such as neural tube defects and Down syndrome. Abnormal AFP levels can prompt further diagnostic procedures like ultrasound or amniocentesis. In non-pregnant individuals, AFP serves as a tumor marker for diagnosing and monitoring cancers, particularly liver, ovarian, and testicular cancers. Elevated AFP levels can also indicate chronic liver conditions like cirrhosis and hepatitis, which increase the risk of liver cancer. The test involves a simple blood draw and provides crucial information when combined with other diagnostic tools. While not definitive on its own, the AFP test aids in diagnosis, treatment monitoring, and early detection of potential health issues.

Price of test:£94

The lowest price from the last 30 days: £94

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

Alpha-fetoprotein (AFP) testing serves multiple critical roles in healthcare:

- Pregnancy Screening: Detects potential birth defects and genetic disorders, such as neural tube defects and Down syndrome, through abnormal AFP levels.
- Cancer Diagnosis and Monitoring: High AFP levels can indicate liver, ovarian, or testicular cancers, aiding in diagnosis and treatment monitoring.
- Chronic Liver Conditions: Elevated AFP levels may signal liver diseases like cirrhosis or hepatitis, indicating increased cancer risk.

AFP tests, while not definitive alone, are vital in conjunction with other diagnostic tools.

Who Should Get Tested

Alpha-fetoprotein (AFP) testing is essential for specific groups:

- Pregnant Women: Used to screen for birth defects and genetic disorders. Abnormal levels may indicate neural tube defects or Down syndrome.

- Cancer Patients: Helps diagnose and monitor liver, ovarian, or testicular cancers. Elevated AFP levels can suggest cancer presence or progression.

- Individuals with Chronic Liver Conditions: Cirrhosis or hepatitis can raise AFP levels, indicating a higher risk of liver cancer.

AFP tests guide further diagnostics and monitor treatment effectiveness, offering crucial insights for healthcare decisions.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for interpreting the significance of Alpha-fetoprotein (AFP) levels. Here's a brief guide:

- Normal Levels: In non-pregnant adults, AFP levels are typically low, under 8 ng/mL. During pregnancy, they range from 0 to 2.5 ng/mL.

- Elevated Levels: High AFP can indicate:
- Cancer: Liver, ovarian, or testicular.
- Liver Diseases: Cirrhosis or hepatitis.
- Pregnancy: Potential birth defects or genetic disorders.

- Specific Indications: Very high AFP often suggests liver cancer; abnormal levels in pregnancy may indicate complications or genetic issues.

Further testing is essential for confirmation and monitoring treatment effectiveness.

Price of test:£94

The lowest price from the last 30 days: £94

AI-Powered Insights and Expert Validation

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