The Alternaria tenuis IgG test is a quantitative immunoassay designed to measure allergen-specific IgG antibodies in serum, assessing immune response to Alternaria tenuis mold. Found in both outdoor and indoor environments, this mold can trigger allergic reactions. While the clinical significance of IgG antibodies is not fully established, the test can offer insights into exposure levels. It is recommended for use by specialists who can interpret results within the context of a patient's health and exposure history. The test employs the ImmunoCAP Fluorescent Enzyme Immunoassay (FEIA) method, requiring a serum sample collected in a serum separator tube. Results are quantified in micrograms per milliliter, with values below 2.00 mcg/mL considered undetectable. The test's utility lies in monitoring exposure rather than diagnosing allergic conditions, as IgG presence alone does not confirm allergies. Interpretation should consider potential false positives, especially in patients with high serum IgE levels.
The Alternaria tenuis IgG test is a quantitative immunoassay designed to measure allergen-specific IgG antibodies in serum, assessing immune response to Alternaria tenuis mold. Found in both outdoor and indoor environments, this mold can trigger allergic reactions. While the clinical significance of IgG antibodies is not fully established, the test can offer insights into exposure levels. It is recommended for use by specialists who can interpret results within the context of a patient's health and exposure history. The test employs the ImmunoCAP Fluorescent Enzyme Immunoassay (FEIA) method, requiring a serum sample collected in a serum separator tube. Results are quantified in micrograms per milliliter, with values below 2.00 mcg/mL considered undetectable. The test's utility lies in monitoring exposure rather than diagnosing allergic conditions, as IgG presence alone does not confirm allergies. Interpretation should consider potential false positives, especially in patients with high serum IgE levels.
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The Alternaria tenuis IgG test is a quantitative immunoassay used to measure allergen-specific IgG antibodies in serum, assessing immune response to Alternaria tenuis mold. Key points include:
- Clinical Utility: Useful in specific cases; results must be interpreted by specialists considering patient health and exposure history. IgG presence alone doesn't indicate allergy.
- Methodology: Involves serum collection, storage, and ImmunoCAP FEIA procedure to measure fluorescence, indicating IgG levels.
- Specimen Requirements: Serum in SST, 0.2 mL minimum, refrigerated transport.
- Turnaround Time: Typically 1-8 days.
- Clinical Context: IgG presence doesn't confirm allergy; consider exposure, symptoms, and health. False positives possible with high IgE levels.
The Alternaria tenuis IgG test measures allergen-specific IgG antibodies in serum, offering insights into exposure and potential allergic reactions. It's useful in specific clinical contexts, ordered by specialists aware of its limitations. Key points include:
- Specimen Collection: Serum sample, ideally 0.5 mL.
- Storage: Refrigerate; stable for up to 2 weeks.
- Assay Procedure: Uses ImmunoCAP FEIA for quantitative results.
- Interpretation: Values <2.00 mcg/mL are undetectable; higher values indicate presence.
- Clinical Context: Results must be interpreted with patient history and health in mind.
Understanding test results for the Alternaria tenuis IgG test involves several key considerations:
- Clinical Context: Results must be interpreted alongside the patient's exposure history and symptoms. The presence of IgG antibodies alone does not confirm an allergy.
- Reference Ranges: Normal ranges indicate expected results for individuals without unusual exposure. These ranges lack disease-associated significance.
- False Positives: Elevated serum IgE levels can lead to false-positive results due to nonspecific binding.
- Specialist Guidance: Only specialists should order this test, ensuring results are contextualized within the patient's overall health.
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