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  3. anti HBc IgG/IgM:

anti HBc IgG/IgM:

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The hepatitis B surface antigen (HBsAg) is most frequently used to screen for the presence of this infection. It is the first detectable viral antigen to appear during infection. However, early in an infection, this antigen may not be present and it may be undetectable later in the infection as it is being cleared by the host. The infectious virion contains an inner "core particle" enclosing viral genome. The icosahedral core particle is made of 180 or 240 copies of core protein, alternatively known as hepatitis B core antigen, or HBcAg. During this 'window' in which the host remains infected but is successfully clearing the virus, IgM antibodies to the hepatitis B core antigen (anti-HBc IgM) may be the only serological evidence of disease. Therefore most hepatitis B diagnostic panels contain HBsAg and total anti-HBc(both IgM and IgG).

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Anti-HBc IgM test is designed to detect the presence of antibodies produced by the body in response to a hepatitis B virus (HBV) infection. These antibodies specifically target the core of the HBV, providing a means to determine if an individual has been exposed to the virus. The test helps in distinguishing between different phases of the infection and understanding the body's immune response to HBV.

Who Should Get Tested

Individuals who show symptoms of hepatitis, those who have been potentially exposed to the hepatitis B virus, or those in high-risk groups (like healthcare workers or individuals with multiple sexual partners) should consider getting tested. It's also crucial for those who have not been vaccinated or are unsure of their vaccination status

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

A negative result might indicate the absence of a recent or past HBV infection or that the individual is in the disease's acute phase. A positive result signifies the body's defense against HBV has been activated. The interpretation of the results should be done in conjunction with other tests like HBsAg and anti-HBs to get a comprehensive understanding of the infection's stage and the body's response.

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