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  3. Anti-Thyroid Peroxidase (aTPO)

Anti-Thyroid Peroxidase (aTPO)

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The Anti-Thyroid Peroxidase (aTPO) is included in test packages, which you can buy at a lower price.

Thyroid peroxidase is an enzyime that is required in order for iodine to be added to the protein thyroglobulin, a precursor to the generation of thyroid hormones which are important in the physical growth, brain development and metabolism of the body. If thyroid peroxidase is not produced or blocked by antibodies, hypothyroidism occurs. Symptoms of hypothyroidism include fatigue, weight gain, muscle weakness, increased cholesterol levels, depression and impaired memory.

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Awaiting result:

One day

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Collect material:

Blood

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Purpose of the test

The thyroid peroxidase (TPO) test is designed to detect antibodies against TPO in the blood. TPO is an enzyme found in the thyroid gland and plays a crucial role in the production of thyroid hormones. The presence of these antibodies can indicate an autoimmune disorder affecting the thyroid, such as Hashimoto's disease or Graves' disease.

Who Should Get Tested

Individuals diagnosed with thyroid disease might be recommended to undergo a TPO antibody test to determine the cause. Additionally, pregnant individuals with autoimmune diseases involving the thyroid, like Hashimoto's or Graves' disease, might also be advised to take the test. Some people with TPO antibodies might not have thyroid disease, but the presence of these antibodies can increase the risk of future thyroid disorders.

Preparing for the Test
Fasting
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Depending on the type of cholesterol test, you may be required to fast for 9 to 12 hours before the test. This means avoiding all food and drinks except water. Fasting is usually required for a lipid panel, which measures LDL and HDL cholesterol, and triglycerides.
Medications
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Inform your healthcare provider about any medications you are currently taking, including over-the-counter medications and supplements, as they can affect your test results.
Alcohol
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Avoid alcohol consumption for at least 24 hours before the test, as alcohol can raise triglyceride levels.
Exercise
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Avoid heavy exercise for 24 hours before the test, as this can also affect cholesterol and triglyceride levels.
Smoking
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Avoid smoking or using any nicotine products for at least 30 minutes before the test, as they can temporarily increase cholesterol levels.
Follow instructions
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Follow any specific instructions provided by your healthcare provider, such as the time of day to take the test or any dietary restrictions.
Interpreting Test Results

A positive result, indicating the presence of TPO antibodies, suggests that the cause of thyroid disease is likely an autoimmune disorder. In autoimmune conditions, the immune system produces antibodies that mistakenly target and attack healthy tissue. When these antibodies target the thyroid gland, it can lead to inflammation, potential tenderness, and reduced thyroid function. However, it's important to note that some individuals with TPO antibodies might not have an active thyroid disease.

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