1. Main page
  2. Tests catalogue
  3. Anti-Thyroid Peroxidase (aTPO)

Anti-Thyroid Peroxidase (aTPO)


Take advantage of our packages

The Anti-Thyroid Peroxidase (aTPO) is included in test packages, which you can buy at a lower price.

Thyroid peroxidase is an enzyime that is required in order for iodine to be added to the protein thyroglobulin, a precursor to the generation of thyroid hormones which are important in the physical growth, brain development and metabolism of the body. If thyroid peroxidase is not produced or blocked by antibodies, hypothyroidism occurs. Symptoms of hypothyroidism include fatigue, weight gain, muscle weakness, increased cholesterol levels, depression and impaired memory.

More arrow

Awaiting result:

One day


Collect material:




Learn more
Purpose of the test

The thyroid peroxidase (TPO) test is designed to detect antibodies against TPO in the blood. TPO is an enzyme found in the thyroid gland and plays a crucial role in the production of thyroid hormones. The presence of these antibodies can indicate an autoimmune disorder affecting the thyroid, such as Hashimoto's disease or Graves' disease.

Who Should Get Tested

Individuals diagnosed with thyroid disease might be recommended to undergo a TPO antibody test to determine the cause. Additionally, pregnant individuals with autoimmune diseases involving the thyroid, like Hashimoto's or Graves' disease, might also be advised to take the test. Some people with TPO antibodies might not have thyroid disease, but the presence of these antibodies can increase the risk of future thyroid disorders.

Preparing for the Test
Depending on the type of cholesterol test, you may be required to fast for 9 to 12 hours before the test. This means avoiding all food and drinks except water. Fasting is usually required for a lipid panel, which measures LDL and HDL cholesterol, and triglycerides.
Inform your healthcare provider about any medications you are currently taking, including over-the-counter medications and supplements, as they can affect your test results.
Avoid alcohol consumption for at least 24 hours before the test, as alcohol can raise triglyceride levels.
Avoid heavy exercise for 24 hours before the test, as this can also affect cholesterol and triglyceride levels.
Avoid smoking or using any nicotine products for at least 30 minutes before the test, as they can temporarily increase cholesterol levels.
Follow instructions
Follow any specific instructions provided by your healthcare provider, such as the time of day to take the test or any dietary restrictions.
Interpreting Test Results

A positive result, indicating the presence of TPO antibodies, suggests that the cause of thyroid disease is likely an autoimmune disorder. In autoimmune conditions, the immune system produces antibodies that mistakenly target and attack healthy tissue. When these antibodies target the thyroid gland, it can lead to inflammation, potential tenderness, and reduced thyroid function. However, it's important to note that some individuals with TPO antibodies might not have an active thyroid disease.

AI-Powered Insights and Expert Validation
Advanced AI Interpretation
Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyzes laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognized medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.
Expert Doctor Confirmation
While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.
Language Model and Trusted Sources
At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.