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Anticardiolipin IgG

Anticardiolipin IgG

The anticardiolipin IgM test is a laboratory diagnostic tool used to detect IgM antibodies against cardiolipin in the blood. Cardiolipin is a phospholipid crucial for cell membrane structure and function. The presence of these antibodies indicates an autoimmune response where the immune system mistakenly targets the body's own cardiolipins. This test is particularly significant in diagnosing antiphospholipid syndrome (APS), a condition associated with excessive blood clotting and recurrent miscarriages. It is often ordered when unexplained blood clots, recurrent miscarriages, or symptoms of autoimmune disorders like systemic lupus erythematosus (SLE) are present. A positive result suggests an increased risk of thrombotic events and pregnancy complications, although transient antibodies due to infections may also yield positive results. The test involves a simple blood draw, analyzed using an enzyme-linked immunosorbent assay (ELISA). Follow-up testing may be necessary to confirm persistent antibodies and ensure accurate diagnosis.

Price of test:£68

The lowest price from the last 30 days: £68

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The anticardiolipin IgM test is a diagnostic tool used to detect IgM antibodies against cardiolipin, a phospholipid crucial for cell membranes. These antibodies are autoantibodies that mistakenly target the body's own cardiolipins, leading to conditions like excessive blood clotting and recurrent miscarriages. The test is used to diagnose:

- Unexplained blood clots
- Recurrent miscarriages
- Autoimmune disorders

A positive result suggests antiphospholipid syndrome, increasing the risk of thrombotic events and pregnancy complications. Blood is drawn and analyzed using ELISA, with minimal risks involved.

Who Should Get Tested

The anticardiolipin IgM test is vital for diagnosing conditions linked to excessive blood clotting and recurrent miscarriages. It detects IgM antibodies against cardiolipin, a crucial cell membrane component. This test is particularly relevant for:

- Unexplained blood clots, such as DVT or PE.
- Women with recurrent miscarriages.
- Individuals with autoimmune disorders like SLE.

A positive result suggests antiphospholipid syndrome, increasing the risk of thrombotic events and pregnancy complications. Blood is drawn for analysis, with minimal risks like bruising. Follow-up testing confirms persistent antibodies.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the anticardiolipin IgM test involves interpreting the presence and concentration of IgM antibodies against cardiolipin. Here's a brief overview:

- Negative Result: No IgM antibodies detected; doesn't rule out other conditions.
- Positive Result: Indicates presence of antibodies, suggesting antiphospholipid syndrome, increased clotting risk, or recurrent miscarriages.
- Titer Levels: Low to moderate may be insignificant; high levels suggest a stronger autoimmune response.

Clinical implications include potential diagnoses of antiphospholipid syndrome, thrombotic events, and autoimmune disorders.

Price of test:£68

The lowest price from the last 30 days: £68

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