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Apolipoprotein B

Apolipoprotein B

The Apolipoprotein B (ApoB) test is a crucial diagnostic tool for evaluating cardiovascular disease (CVD) risk. ApoB is the main protein in low-density lipoprotein (LDL), often termed "bad cholesterol," and each LDL particle contains one ApoB molecule. This makes ApoB a precise indicator of LDL levels. The test is particularly beneficial for individuals with metabolic syndrome, diabetes, or a family history of coronary artery disease, as it provides a more accurate assessment of cardiovascular health than traditional lipid profiles. The test involves a simple blood draw, with results expressed in milligrams per deciliter (mg/dL). High ApoB levels suggest an increased number of LDL particles, elevating the risk of atherosclerosis, heart attacks, and strokes. Conversely, low levels indicate a reduced risk. The test does not require fasting and is cost-effective, typically under $100. It is especially useful in populations where traditional lipid tests may not fully capture cardiovascular risk.

Price of test:£63

The lowest price from the last 30 days: £63

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Apolipoprotein B (ApoB) test is crucial for evaluating cardiovascular disease (CVD) risk. By measuring ApoB, healthcare providers gain insights into cardiovascular health beyond traditional lipid profiles, especially for those with metabolic syndrome or a family history of coronary artery disease. The test involves analyzing a blood sample to determine ApoB concentration, directly reflecting atherogenic particle levels. Key points include:

- Risk Prediction: Offers a more accurate CVD risk assessment.
- Interpretation: Results in mg/dL, with specific reference intervals.
- Management: High levels may lead to lifestyle changes and statin therapy.
- Practical Considerations: No fasting required; results in 1-2 days.

Who Should Get Tested

Apolipoprotein B (ApoB) testing is crucial for assessing cardiovascular risk, especially in individuals with metabolic syndrome, diabetes, or a family history of coronary artery disease. This test measures ApoB levels, providing a direct indicator of circulating LDL particles, often referred to as "bad cholesterol." Key points include:

- Purpose: Evaluates cardiovascular disease risk more accurately than traditional lipid profiles.
- Procedure: Involves a blood sample to measure ApoB concentration.
- Significance: High ApoB levels indicate increased atherosclerosis risk.
- Interpretation: Results vary by age, with specific desirable and high thresholds.
- Management: High levels may require lifestyle changes and statin therapy.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for Apolipoprotein B (ApoB) is crucial for evaluating cardiovascular health. Here’s a concise guide:

- Purpose: Assesses cardiovascular disease risk by measuring ApoB, a key protein in LDL ("bad cholesterol").
- Clinical Significance: High ApoB levels indicate increased LDL particles, raising heart disease risk.
- Interpretation:
- Children/Adolescents: Desirable <90 mg/dL; High ≥110 mg/dL.
- Adults: Desirable <90 mg/dL; Very high ≥140 mg/dL.
- Management: High levels may require lifestyle changes and statin therapy.
- Practical Considerations: No fasting needed; results in 1-2 days.

Price of test:£63

The lowest price from the last 30 days: £63

AI-Powered Insights and Expert Validation

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