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Blood Group
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Blood typing is a method to tell what type of blood you have. Blood typing is done so you can safely donate your blood or receive a blood transfusion. It is also done to see if you have a substance called Rh factor on the surface of your red blood cells.
Your blood type is based on whether or not certain proteins are on your red blood cells. These proteins are called antigens. Your blood type (or blood group) depends on what types your parents passed down to you.The placement of the A and B antigens is dependent upon the existence of a substrate produced by the Hh blood group system (ISBT # 018). Some individuals have weakened or variant expression of A and/or B which can be attributed to inheritance of variant forms of transferases. Those individuals that have neither transferases, inheritors of two amorph genes, are group O. To date, 14 A alleles, 14 B alleles and 8 O alleles have been identified at the molecular level and more remain to be found. The ABO antigens, as stated above are not restricted to the red blood cell membrane but can be found in saliva and all body fluids except spinal fluid if the individual has inherited a secretor gene. The antigens are also found on most epithelial and endothelial cells. It also appears on lymphocytes and platelets as it is adsorbed from the plasma. Alterations of ABH expression have been found in various forms of cancer. Furthermore, antigens of the ABO system may play a role in resistance to bacteria or viruses.
Blood typing is a method to tell what type of blood you have. Blood typing is done so you can safely donate your blood or receive a blood transfusion. It is also done to see if you have a substance called Rh factor on the surface of your red blood cells.
Your blood type is based on whether or not certain proteins are on your red blood cells. These proteins are called antigens. Your blood type (or blood group) depends on what types your parents passed down to you.The placement of the A and B antigens is dependent upon the existence of a substrate produced by the Hh blood group system (ISBT # 018). Some individuals have weakened or variant expression of A and/or B which can be attributed to inheritance of variant forms of transferases. Those individuals that have neither transferases, inheritors of two amorph genes, are group O. To date, 14 A alleles, 14 B alleles and 8 O alleles have been identified at the molecular level and more remain to be found. The ABO antigens, as stated above are not restricted to the red blood cell membrane but can be found in saliva and all body fluids except spinal fluid if the individual has inherited a secretor gene. The antigens are also found on most epithelial and endothelial cells. It also appears on lymphocytes and platelets as it is adsorbed from the plasma. Alterations of ABH expression have been found in various forms of cancer. Furthermore, antigens of the ABO system may play a role in resistance to bacteria or viruses.
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Blood typing is a crucial procedure that determines an individual's blood type. It is essential for ensuring the safe donation or receipt of blood during transfusions. The test also identifies the presence or absence of the Rh factor on the surface of red blood cells. Blood type is determined based on specific proteins, called antigens, present on the red blood cells.
Blood typing is recommended for individuals who intend to donate blood or those who may require a blood transfusion. It's also vital during pregnancy to prevent complications like severe anemia in the newborn and jaundice. Knowing one's blood type ensures that they receive compatible blood, reducing the risk of adverse reactions.
The results will indicate the individual's ABO blood type (A, B, AB, or O) and their Rh factor (positive or negative). It's essential to understand these results as they dictate which blood type an individual can safely receive. For instance, a person with type A blood can only receive type A or O blood. The results also highlight the significance of the universal donor, type O, which can be given to anyone regardless of their blood type.