CMV IgG

The Cytomegalovirus (CMV) IgM antibody test is a diagnostic tool used to identify recent or active CMV infections by detecting IgM antibodies in a patient's serum. CMV is a widespread virus that can cause mild to severe symptoms, especially in individuals with weakened immune systems. The test is crucial for diagnosing acute or recent infections, as a positive result indicates a primary, reactivated, or reinfection with CMV. However, a negative result does not entirely exclude a primary infection, as some individuals may not produce detectable IgM antibodies early on. The test is performed using a semi-quantitative chemiluminescent immunoassay, requiring a serum sample. While the test is valuable, it has limitations, such as potential false positives due to cross-reactivity with other viruses and the inability to provide quantitative antibody levels. Therefore, results should be interpreted alongside clinical symptoms and other laboratory findings for accurate diagnosis and management of CMV infections.

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Price of test:£68

The lowest price from the last 30 days: £68

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The CMV IgM antibody test is crucial for diagnosing recent CMV infections. It detects IgM antibodies, indicating a primary, reactivated, or reinfection. However, a negative result doesn't entirely rule out infection, especially in early stages or immunocompromised patients.

- Primary Infection: IgM may be undetectable early on.
- Reactivation: Positive results can indicate latent infection reactivation.
- Immunocompromised Patients: May show delayed seroconversion.
- Clinical Correlation: Should be used with clinical data and other tests.

Understanding these factors ensures accurate diagnosis and management.

Who Should Get Tested

The CMV IgG test is vital for diagnosing past CMV exposure. It measures IgG antibodies, indicating immunity. Key groups needing testing include:

- Pregnant Women: Positive results risk congenital CMV, affecting newborns.
- Immune-Compromised Individuals: Past exposure can lead to severe complications.
- Organ Transplant Recipients: Screening prevents post-transplant infections.

Limitations include undetectable antibodies in early infection and potential cross-reactivity. Additional tests like CMV IgM and PCR help confirm active infections. Despite limitations, the CMV IgG test is crucial for managing CMV, ensuring optimal patient care.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results for the CMV IgM antibody test is crucial for accurate diagnosis and management. This test detects IgM antibodies, indicating recent or current CMV infection. Key points include:

- Positive Result: Suggests primary, reactivated, or reinfection with CMV.
- Negative Result: Does not entirely rule out infection, especially in early stages.
- Primary Infection: IgM may be undetectable early on.
- Reactivation: Positive results can indicate reactivation, especially in immunocompromised patients.
- Clinical Correlation: Always interpret results alongside clinical symptoms and history.
- Limitations: Be aware of potential false positives and negatives due to cross-reactivity.

Price of test:£68

The lowest price from the last 30 days: £68

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