Clove IgE

The cobalt urine test is a vital diagnostic tool used to assess cobalt exposure, crucial in both clinical and occupational settings. Cobalt, while essential as a component of vitamin B12, can be hazardous in high concentrations. This test is particularly important for individuals exposed to cobalt through industrial activities, such as manufacturing hard alloys, glass, and pigments, or those with cobalt-based prosthetic implants. It helps detect potential metallosis from implant wear. The test requires a urine specimen, collected either randomly or over 24 hours, ensuring no preservatives are present to avoid interference with results. Inductively-Coupled Plasma/Mass Spectrometry (ICP/MS) is the preferred method for its sensitivity and accuracy. Elevated cobalt levels in urine can indicate excessive exposure, necessitating protective measures. Reference ranges vary, with occupational exposure levels set at 15.0 mcg/L or above. Proper specimen collection and handling are crucial to avoid contamination, ensuring reliable results and safeguarding health.

Price of test:£34

The lowest price from the last 30 days: £34

Awaiting result:

One day

Collect material:

Blood

Prepare:

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Purpose of the test

The cobalt urine test is vital for detecting cobalt exposure in clinical and occupational settings. It assesses exposure from industrial activities, prosthetic implants, or environmental sources. Key points include:

- Specimen Collection: Use clean containers; collect at week's end for random tests or over 24 hours.
- Volume Requirements: 1.5 mL for random, 0.5 mL for 24-hour collections.
- Storage: Stable for 14 days at room temperature, refrigerated, or frozen.
- Methodology: Conducted via ICP/MS for precise results.
- Interpretation: Elevated levels indicate exposure or implant wear.
- Precautions: Avoid contamination; use metal-free containers.

Who Should Get Tested

The Clove IgE test is essential for individuals experiencing symptoms like redness, irritation, or swelling after clove exposure. It measures IgE antibodies in the blood to confirm clove allergies. Key steps include:

- Sample Collection: Blood is drawn and placed in a serum gel tube.
- Centrifugation: Separates serum from other components.
- Aliquoting: Serum is placed in a vial for testing.
- Testing: Uses FEIA to detect IgE binding to clove.
- Detection: Measures fluorescence to determine IgE levels.

Results guide allergy management, ensuring effective treatment.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for interpreting cobalt urine test outcomes. Here’s a brief guide:

- Occupational Exposure: Elevated cobalt levels may indicate prolonged exposure, necessitating protective measures.
- Prosthetic Implants: Increased levels suggest implant wear, potentially leading to metallosis.
- Reference Ranges:
- Environmental: 1.0-2.0 mcg/L
- Occupational: ≥15.0 mcg/L
- Prosthetic Wear: >20 mcg/g creatinine

Accurate interpretation relies on context, ensuring effective monitoring and prevention of health risks associated with cobalt exposure.

Price of test:£34

The lowest price from the last 30 days: £34

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