1. Main page
    arrow-right-icon
  2. Tests catalogue
    arrow-right-icon
  3. Cocaine metabolites

Cocaine metabolites

chart-icon

Take advantage of our packages

The Cocaine metabolites is included in test packages, which you can buy at a lower price.

Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium.

More arrow
clock-icon

Awaiting result:

One day

syringe-icon

Collect material:

Blood

sun-icon

Prepare:

Learn more
Purpose of the test

The cocaine screen is a diagnostic test designed to determine if an individual has recently used cocaine. This test can detect the presence of cocaine or its metabolites in various samples, including urine, saliva, blood, hair, or sweat. The primary metabolites of cocaine that the test looks for are benzoylecgonine and ecgonine methyl ester, with the former being the most commonly tested.

Who Should Get Tested

Several scenarios might necessitate a cocaine screen. Individuals applying for jobs or insurance policies that require drug testing, those on parole, or those suspected of driving under the influence of drugs might be tested. Additionally, healthcare providers might order the test if they suspect cocaine abuse, if a patient presents in the emergency room with symptoms indicative of drug abuse, or if the patient is at a drug treatment clinic.

Blood Test Preparation Guidelines
Time of day
icon
It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
icon
It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
icon
Drinking water prior to testing can help with sample collection.
Other factors
icon
Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
icon
Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
icon
High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

The results of a cocaine screen are typically reported as either positive (indicating the presence of cocaine or its metabolites) or negative (no evidence of cocaine in the body). The exact interpretation depends on the cutoff number, which indicates the concentration of the substance in the sample. It's important to note that rapid screening tests, while quick, are not as accurate as lab tests. Therefore, positive results from rapid tests should always be confirmed in a lab for accuracy.

AI-Powered Insights and Expert Validation
Advanced AI Interpretation
Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.
Expert Doctor Confirmation
While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.
Language Model and Trusted Sources
At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.