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Complement C1Q

Complement C1Q

The complement C2 functional test is a vital laboratory assessment used to evaluate the activity and functionality of the complement component C2 in blood. This test is essential for understanding the immune system's response to pathogens and its involvement in autoimmune diseases. Complement C2 is a crucial element in the classical and lectin pathways of the complement system, facilitating the activation of C3 and C5 convertases, which are pivotal for immune responses such as inflammation, opsonization, and the membrane-attack phase. The test employs various techniques, including ELISA and hemolytic assays, to assess C2 activity. Results can indicate normal, deficient, or equivocal C2 activity, aiding in diagnosing conditions like systemic lupus erythematosus and susceptibility to infections. Proper sample handling is crucial for accurate results. The test's findings can guide treatment strategies and contribute to drug development, highlighting its significance in clinical diagnostics and research.

Price of test:£126

The lowest price from the last 30 days: £126

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The complement C2 functional test is essential for evaluating the activity of complement component C2 in the blood, crucial for immune response and autoimmune disease assessment. Key points include:

- Importance: C2 is vital in the classical and lectin pathways, aiding immune responses.
- Methodology: Utilizes assays like ELISA and CH50 to assess C2 activity.
- Clinical Significance: Identifies deficiencies linked to infections and autoimmune diseases.
- Sample Handling: Proper processing is crucial for accurate results.
- Interpretation: Results guide diagnosis and treatment, highlighting C2's role in disease progression.

Who Should Get Tested

The complement C2 functional test is essential for evaluating immune response and diagnosing autoimmune diseases. It assesses the activity of complement component C2, crucial in the classical and lectin pathways. Key points include:

- Methodology: Utilizes assays like ELISA and hemolytic assays.
- Analysis: Results can be normal, abnormal, or equivocal.
- Clinical Significance: Links to infections and autoimmune diseases like SLE.
- Sample Handling: Requires precise processing to ensure accuracy.
- Interpretation: Low C2 levels suggest increased infection risk; high levels indicate acute phase response.

This test aids in disease diagnosis and treatment customization.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the complement C2 functional test is essential for evaluating immune response and potential deficiencies. Here's a brief overview:

- Normal Results: Indicate proper complement system function.
- Abnormal Results: Suggest reduced or absent C2 activity, pointing to a deficiency.
- Equivocal Results: May indicate partial deficiency, requiring further investigation.

Clinical significance includes:

- Infections: Low C2 levels increase susceptibility, especially to encapsulated bacteria.
- Autoimmune Diseases: Linked to conditions like systemic lupus erythematosus.
- Biomarker Potential: Useful in predicting diseases and guiding treatment strategies.

Price of test:£126

The lowest price from the last 30 days: £126

AI-Powered Insights and Expert Validation

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