Complement C3

The complement C4 test is an essential diagnostic tool for evaluating the immune system, particularly in autoimmune disorders and inflammatory conditions. It measures the levels of complement component 4 (C4), a protein integral to the innate immune response. This test is primarily used to diagnose and monitor autoimmune diseases like systemic lupus erythematosus (SLE), rheumatoid arthritis, and hereditary angioedema, as well as to assess kidney function and inflammatory activity. Conducted via a simple blood draw, the test provides insights into the immune system's response to various diseases. Normal C4 levels range from 16 to 48 mg/dL, with deviations indicating potential health issues. Low levels may suggest autoimmune diseases or infections, while high levels could indicate inflammation or cancer. The C4 test is often used alongside other tests, such as the total complement activity test (CH50) and complement C3 test, to offer a comprehensive view of immune function and guide treatment strategies.

Price of test:£94

The lowest price from the last 30 days: £94

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The complement C4 test is essential for evaluating immune function, particularly in autoimmune and inflammatory conditions. It measures complement component 4 levels, aiding in diagnosing and monitoring diseases like:

- Systemic Lupus Erythematosus (SLE): Low C4 levels indicate active disease.
- Rheumatoid Arthritis: Low levels suggest active disease.
- Hereditary Angioedema: Characterized by low C4 levels.
- Glomerulonephritis: Associated with low C4 levels.

The test involves a simple blood draw, with results indicating immune response status. It is often used alongside other tests for comprehensive immune assessment.

Who Should Get Tested

The complement C4 test is essential for diagnosing and monitoring autoimmune and inflammatory conditions. It measures complement component 4, a protein crucial to the immune system. Key uses include:

- Autoimmune Diseases: Low C4 levels often indicate active systemic lupus erythematosus (SLE) or rheumatoid arthritis.
- Inflammatory Conditions: Hereditary angioedema and glomerulonephritis are linked to low C4 levels.
- Other Conditions: Bacterial infections and hepatitis can also lower C4 levels.

This test, often combined with others, provides insights into immune function, guiding treatment strategies effectively.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the complement C4 test is essential for interpreting immune system function. This test measures C4 protein levels, aiding in diagnosing autoimmune and inflammatory conditions.

- Normal Range: Typically 16-48 mg/dL for adults.
- High Levels: May indicate cancer, ulcerative colitis, or inflammation.
- Low Levels: Suggest autoimmune diseases like SLE, rheumatoid arthritis, or hereditary angioedema.

Interpreting these results helps healthcare providers assess disease activity and treatment effectiveness, guiding patient care strategies.

Price of test:£94

The lowest price from the last 30 days: £94

AI-Powered Insights and Expert Validation

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