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Calcium is the most plentiful mineral in the human body. Ninety-nine percent is stored in the bones and teeth where it provides structure and functionality. The remaining 1% of the body's calcium is necessary for vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Serum calcium levels do not fluctuate in response to dietary intake. Bone tissue is the reservoir for calcium and helps to maintain concentrations in the blood, the muscle, and intercellular fluids. As humans age, the bone is constantly being laid down and reabsorbed. In growing children, bone formation exceeds that of bone resorption. In young and middle-aged adults, the bone formation and resorption is about equal. In older adults, especially in post-menopausal women, bone loss exceeds that of bone formation, which is why their risk for osteoporosis continues to increase as they age. The Corrected Calcium test aims to mathematically correct the measured total calcium for reduced albumin levels, especially in cases where total calcium is normal but there's suspected hypercalcemia with concurrent hypoalbuminemia.
Calcium is the most plentiful mineral in the human body. Ninety-nine percent is stored in the bones and teeth where it provides structure and functionality. The remaining 1% of the body's calcium is necessary for vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Serum calcium levels do not fluctuate in response to dietary intake. Bone tissue is the reservoir for calcium and helps to maintain concentrations in the blood, the muscle, and intercellular fluids. As humans age, the bone is constantly being laid down and reabsorbed. In growing children, bone formation exceeds that of bone resorption. In young and middle-aged adults, the bone formation and resorption is about equal. In older adults, especially in post-menopausal women, bone loss exceeds that of bone formation, which is why their risk for osteoporosis continues to increase as they age. The Corrected Calcium test aims to mathematically correct the measured total calcium for reduced albumin levels, especially in cases where total calcium is normal but there's suspected hypercalcemia with concurrent hypoalbuminemia.
Awaiting result:
One day
Collect material:
Blood
Prepare:
The Corrected Calcium test aims to mathematically correct the measured total calcium for reduced albumin levels, especially in cases where total calcium is normal but there's suspected hypercalcemia with concurrent hypoalbuminemia.
Patients with suspected hypercalcemia and concurrent hypoalbuminemia, especially when the total calcium appears normal and an ionized calcium test cannot be obtained. It's important to note that the correction is not valid for certain groups, including those with chronic kidney disease, end-stage renal disease, or pregnant women
The results will provide a corrected calcium value, which has been adjusted for albumin levels. It's crucial to understand that the formula used for correction hasn't been validated for pediatric subjects. If there are any discrepancies or doubts, confirmatory testing with ionized calcium is advised.
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