Corrected Calcium
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Calcium is the most plentiful mineral in the human body. Ninety-nine percent is stored in the bones and teeth where it provides structure and functionality. The remaining 1% of the body's calcium is necessary for vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Serum calcium levels do not fluctuate in response to dietary intake. Bone tissue is the reservoir for calcium and helps to maintain concentrations in the blood, the muscle, and intercellular fluids. As humans age, the bone is constantly being laid down and reabsorbed. In growing children, bone formation exceeds that of bone resorption. In young and middle-aged adults, the bone formation and resorption is about equal. In older adults, especially in post-menopausal women, bone loss exceeds that of bone formation, which is why their risk for osteoporosis continues to increase as they age. The Corrected Calcium test aims to mathematically correct the measured total calcium for reduced albumin levels, especially in cases where total calcium is normal but there's suspected hypercalcemia with concurrent hypoalbuminemia.
Calcium is the most plentiful mineral in the human body. Ninety-nine percent is stored in the bones and teeth where it provides structure and functionality. The remaining 1% of the body's calcium is necessary for vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Serum calcium levels do not fluctuate in response to dietary intake. Bone tissue is the reservoir for calcium and helps to maintain concentrations in the blood, the muscle, and intercellular fluids. As humans age, the bone is constantly being laid down and reabsorbed. In growing children, bone formation exceeds that of bone resorption. In young and middle-aged adults, the bone formation and resorption is about equal. In older adults, especially in post-menopausal women, bone loss exceeds that of bone formation, which is why their risk for osteoporosis continues to increase as they age. The Corrected Calcium test aims to mathematically correct the measured total calcium for reduced albumin levels, especially in cases where total calcium is normal but there's suspected hypercalcemia with concurrent hypoalbuminemia.
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Purpose of the test
The Corrected Calcium test aims to mathematically correct the measured total calcium for reduced albumin levels, especially in cases where total calcium is normal but there's suspected hypercalcemia with concurrent hypoalbuminemia.
Who Should Get Tested
Patients with suspected hypercalcemia and concurrent hypoalbuminemia, especially when the total calcium appears normal and an ionized calcium test cannot be obtained. It's important to note that the correction is not valid for certain groups, including those with chronic kidney disease, end-stage renal disease, or pregnant women
Blood Test Preparation Guidelines
Time of day
It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
Drinking water prior to testing can help with sample collection.
Other factors
Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results
The results will provide a corrected calcium value, which has been adjusted for albumin levels. It's crucial to understand that the formula used for correction hasn't been validated for pediatric subjects. If there are any discrepancies or doubts, confirmatory testing with ionized calcium is advised.
AI-Powered Insights and Expert Validation
Advanced AI Interpretation
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Expert Doctor Confirmation
While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.
Language Model and Trusted Sources
At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.
