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Crosslaps-serum CTX


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The Crosslaps-serum CTX is included in test packages, which you can buy at a lower price.

C-Telopeptide (CTx) is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss.

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Purpose of the test

The Beta-CrossLaps test, also known as Beta-C-terminal telopeptide (CTx) test, is used to monitor antiresorptive therapies such as bisphosphonates and hormone replacement therapy in postmenopausal women treated for osteoporosis and individuals diagnosed with osteopenia. Additionally, it serves as an adjunct in diagnosing medical conditions associated with increased bone turnover. The test specifically measures the degradation of mature type I collagen, which is released into the bloodstream during bone resorption.

Who Should Get Tested

This test is particularly beneficial for postmenopausal women undergoing treatment for osteoporosis, individuals diagnosed with osteopenia, and those suspected of having medical conditions associated with increased bone turnover. These conditions include hyperthyroidism, hyperparathyroidism, osteomalacia, rickets, Paget disease, multiple myeloma, and bone metastases, among others.

Blood Test Preparation Guidelines
Time of day
It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
Drinking water prior to testing can help with sample collection.
Other factors
Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Elevated levels of Beta-C-terminal telopeptide (CTx) indicate increased bone resorption. High levels are associated with conditions like osteoporosis, osteopenia, Paget disease, hyperthyroidism, and hyperparathyroidism. For patients on antiresorptive agents, a decrease of 25% or more from baseline beta-CTx levels 3 to 6 months after starting therapy signifies an adequate therapeutic response. The test results can provide insights into the effectiveness of treatments and the state of bone health in the patient.

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