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Cyclosporin Level (Monoclonal)

Cyclosporin Level (Monoclonal)

The CYFRA 21-1 antigen test is a crucial diagnostic tool for monitoring non-small cell lung cancer (NSCLC). It measures cytokeratin 19 fragments in the serum, which are released during cellular apoptosis and abnormal mitosis. As lung cancer remains a leading cause of cancer-related deaths, this test aids in assessing disease progression and treatment response. Elevated CYFRA 21-1 levels often indicate a poor prognosis, while decreasing levels during therapy suggest a positive treatment response. However, the test is not suitable for lung cancer screening and should be used alongside other diagnostic methods. It can also show elevated results in benign respiratory diseases and other cancers. Typically measured using electrochemiluminescence immunoassay, the test requires careful specimen handling to ensure accuracy. Despite its limitations, the CYFRA 21-1 antigen test provides valuable prognostic information, enhancing patient care by helping healthcare providers make informed decisions about treatment strategies for NSCLC, particularly in advanced stages.

Price of test:£702

The lowest price from the last 30 days: £702

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The CYFRA 21-1 antigen test is crucial for monitoring non-small cell lung cancer (NSCLC). It measures cytokeratin 19 fragments in serum, aiding in prognosis and treatment assessment. Key points include:

- Prognostic Value: High pretreatment levels indicate poor prognosis.
- Monitoring: Decreasing levels suggest positive treatment response.
- Limitations: Not definitive for diagnosis; elevated in other conditions.
- Methodology: Uses electrochemiluminescence immunoassay.
- Specimen Handling: Requires careful handling to avoid interference.

This test, while not standalone, is vital for comprehensive NSCLC management.

Who Should Get Tested

The Cyclosporin Level (Monoclonal) test is vital for transplant patients, ensuring cyclosporine levels are safe and effective. Key aspects include:

- Purpose: Monitors cyclosporine to prevent organ rejection and manage side effects.
- Sample Collection: Whole blood in EDTA tube, drawn before the next dose.
- Analytical Method: Uses monoclonal immunoassay and LC-MS/MS for accuracy.
- Therapeutic Ranges: Varies by transplant type; generally 100-400 ng/mL.
- Clinical Significance: Optimizes immunosuppression, minimizes toxicity, evaluates compliance, and adjusts dosage.

Despite challenges, this test is crucial for patient care.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the CYFRA 21-1 antigen test involves several key points:

- Elevated Levels: Indicate a potentially unfavorable prognosis in NSCLC patients.
- Decreasing Levels: Suggest a positive response to treatment.
- Normal Results: Do not rule out NSCLC; further investigation is necessary.
- Interference Factors: Hemolyzed, icteric, or lipemic specimens can affect results.
- Clinical Context: Results should be interpreted alongside other clinical evidence.
- Not for Screening: This test is not suitable for lung cancer screening purposes.

Price of test:£702

The lowest price from the last 30 days: £702

AI-Powered Insights and Expert Validation

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Language Model and Trusted Sources

At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

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