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Enhanced Liver Fibrosis

Enhanced Liver Fibrosis

The Enhanced Liver Fibrosis (ELF) test is a non-invasive blood test designed to evaluate liver fibrosis severity, a condition marked by scar tissue accumulation in the liver that can progress to cirrhosis. It is particularly beneficial for managing chronic liver diseases such as those caused by alcohol, viral hepatitis, and non-alcoholic fatty liver disease (NAFLD). The ELF test measures three biomarkers: hyaluronic acid (HA), Type III procollagen peptide (PIIINP), and tissue inhibitor of matrix metalloproteinase 1 (TIMP-1), which are involved in liver extracellular matrix metabolism. By analyzing these markers, the test provides a numerical score indicating fibrosis severity. The ELF test is both diagnostic and prognostic, aiding in patient stratification for treatment decisions and monitoring disease progression. Its non-invasive nature makes it suitable for routine use in primary, secondary, and tertiary care settings, although considerations such as false positives and variations due to age and gender should be noted.

Price of test:£335

The lowest price from the last 30 days: £335

Awaiting result:

7 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Enhanced Liver Fibrosis (ELF) test is a non-invasive diagnostic tool for assessing liver fibrosis severity. It measures three biomarkers: hyaluronic acid, Type III procollagen peptide, and tissue inhibitor of matrix metalloproteinase 1. These markers reflect fibrotic changes in the liver.

- Diagnostic Accuracy: Identifies advanced fibrosis and cirrhosis reliably.
- Prognostic Value: Higher scores indicate increased risk of liver complications.
- Non-Invasive: Simple blood test, ideal for routine monitoring.

Despite its utility, the ELF test has limitations, such as false positives and variations due to age and gender.

Who Should Get Tested

The Enhanced Liver Fibrosis (ELF) test is a crucial tool for assessing liver fibrosis severity. It measures three biomarkers: hyaluronic acid, Type III procollagen peptide, and TIMP-1, providing a numerical score that indicates fibrosis extent. Key applications include:

- Primary Care: Screens for severe liver disease, guiding further evaluation.
- Secondary/Tertiary Care: Monitors fibrosis progression and treatment efficacy.
- Risk Stratification: Identifies patients at risk for advanced fibrosis or cirrhosis.

Despite its accuracy, consider potential false positives and variations due to age and gender.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results from the Enhanced Liver Fibrosis (ELF) test is crucial for managing liver health. The ELF test provides a numerical score indicating the severity of liver fibrosis, aiding in diagnosis and prognosis.

- Score Interpretation: Scores below 9.8 suggest lower risk, while those above 11.29 indicate higher risk of liver complications.
- Diagnostic Use: Accurately identifies advanced fibrosis and cirrhosis.
- Prognostic Value: Higher scores correlate with increased risk of liver-related events.
- Non-Invasive: A simple blood test, ideal for routine monitoring.
- Clinical Application: Useful in primary care for screening and in specialized care for monitoring treatment effectiveness.

Price of test:£335

The lowest price from the last 30 days: £335

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.

Expert Doctor Confirmation

While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.

Language Model and Trusted Sources

At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

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