Fructosamine

The Factor V Leiden test is a genetic diagnostic procedure designed to detect a mutation in the F5 gene, which encodes coagulation factor V. This mutation results in Factor V Leiden, a hereditary blood clotting disorder that elevates the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE). In individuals with this condition, the mutated factor V does not interact properly with activated protein C (APC), leading to excessive clotting. The test identifies whether a person carries one or two copies of the mutated gene, significantly impacting their risk level. Typically, it is recommended for those with a personal or family history of venous thromboembolism (VTE). While many with Factor V Leiden remain asymptomatic, potential symptoms include limb swelling and chest pain, indicative of DVT or PE. Treatment focuses on anticoagulant medications to prevent clot formation, alongside lifestyle modifications to mitigate risks. Understanding and managing Factor V Leiden is vital for preventing severe complications.

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Price of test:£68

The lowest price from the last 30 days: £68

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Factor V Leiden test aims to identify a genetic mutation in the F5 gene, crucial for diagnosing a blood clotting disorder. This mutation can lead to:

- Increased risk of deep vein thrombosis (DVT)
- Higher likelihood of pulmonary embolism (PE)

Diagnosis involves a genetic test to detect the mutated gene, assessing risk levels based on gene copies. Treatment focuses on:

- Anticoagulant medications to prevent clots
- Lifestyle changes to reduce clotting risk

Understanding this condition aids in managing patient care and preventing severe complications.

Who Should Get Tested

The fructosamine test is essential for certain individuals to monitor diabetes management effectively. It provides a snapshot of average blood glucose levels over the past 2 to 3 weeks, crucial for adjusting treatment plans. Key groups who benefit from this test include:

- Patients with diabetes needing short-term glucose monitoring.
- Individuals with conditions affecting red blood cell lifespan, like sickle cell disease.
- Children with type 1 diabetes where HbA1c may be unreliable.

This test aids in preventing complications by ensuring glucose levels remain within a safe range.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results for the Factor V Leiden test is crucial for managing health risks. Here's what you need to know:

- Genetic Mutation: The test identifies a mutation in the F5 gene, linked to increased clotting risk.
- Risk Assessment: One mutated gene copy increases clot risk 10-fold; two copies increase it 60-fold.
- Symptoms: Often asymptomatic, but watch for DVT or PE signs like limb swelling or chest pain.
- Treatment: Anticoagulants manage clot risk but require careful monitoring.
- Prevention: Stay active, avoid smoking, and consult healthcare providers for personalized advice.

Price of test:£68

The lowest price from the last 30 days: £68

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