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Free Kappa Light Chains

Free Kappa Light Chains

The free kappa light chain (FKLC) test is a blood test that measures the levels of kappa free light chains in the serum, which are proteins produced by plasma cells. These cells are vital for the immune system as they produce antibodies. Free light chains are those that do not pair with heavy chains to form complete immunoglobulins and are instead released into the bloodstream. Typically, healthy individuals have low levels of these chains, but elevated levels can indicate plasma cell disorders such as multiple myeloma or MGUS. The FKLC test is crucial for diagnosing and monitoring these conditions, especially when symptoms like bone pain, fatigue, or kidney issues arise. The test involves a simple blood draw, with minimal risks like bruising or lightheadedness. Results are interpreted based on normal ranges and the kappa to lambda ratio, aiding in diagnosis and treatment planning. Additional tests may complement the FKLC test for a comprehensive evaluation.

Price of test:£166

The lowest price from the last 30 days: £166

Awaiting result:

7 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The FKLC test measures kappa free light chains in the blood, aiding in diagnosing plasma cell disorders. Key points include:

- Purpose: Diagnose and monitor conditions like multiple myeloma and MGUS.
- Symptoms: Bone pain, fatigue, anemia, and kidney issues may prompt testing.
- Procedure: Blood sample drawn; no special preparation needed.
- Risks: Minor risks include bleeding and bruising.
- Results: Normal range is 3.3 to 19.4 mg/L; abnormal levels suggest disorders.
- Monitoring: Tracks disease progression and treatment efficacy.
- Additional Tests: Bone marrow biopsy, electrophoresis, and imaging may complement the FKLC test.

Who Should Get Tested

The FKLC test is crucial for diagnosing plasma cell disorders. It measures kappa free light chains in the blood, aiding in the detection of conditions like multiple myeloma and MGUS. Symptoms prompting the test include:

- Bone pain
- Fatigue
- Anemia
- Kidney issues

The test involves a simple blood draw, with minimal risks such as bruising or lightheadedness. Normal kappa levels range from 3.3 to 19.4 mg/L. Abnormal results may indicate plasma cell disorders. Additional tests, like bone marrow biopsy and electrophoresis, may complement the FKLC test for comprehensive diagnosis and monitoring.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for effective diagnosis and treatment planning. The FKLC test measures kappa free light chains in the blood, aiding in the diagnosis of plasma cell disorders. Key points include:

- Normal Range: 3.3 to 19.4 mg/L for kappa light chains.
- Abnormal Levels: May indicate disorders like multiple myeloma or MGUS.
- κ:λ Ratio: An abnormal ratio suggests monoclonal gammopathy.
- Monitoring: Tracks disease progression and treatment efficacy.

Consult your healthcare provider for interpretation and next steps based on your results.

Price of test:£166

The lowest price from the last 30 days: £166

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