Gluten IgE

The Gluten IgG test is a serologic blood test designed to detect gluten-specific IgG antibodies, aiding in the diagnosis of celiac disease, especially in individuals with IgA deficiency. Celiac disease is an autoimmune disorder triggered by gluten consumption, leading to intestinal inflammation and various symptoms like abdominal pain and fatigue. This test is crucial for those unable to produce sufficient IgA antibodies, as it measures IgG antibodies against gluten, indicating an immune response. For accurate results, patients must consume gluten for several weeks before testing. The Gluten IgG test is often used alongside other tests, such as tTG-IgA and DGP-IgG, to provide a comprehensive diagnosis. While positive results suggest an immune reaction, a small intestinal biopsy is typically required for confirmation. The test also helps monitor treatment effectiveness by tracking antibody levels in patients on a gluten-free diet. Despite its utility, the test can yield false positives or negatives, necessitating careful interpretation.

Price of test:£34

The lowest price from the last 30 days: £34

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Gluten IgG test is a serologic blood test designed to detect gluten-specific antibodies, aiding in diagnosing celiac disease. This autoimmune disorder arises in genetically predisposed individuals consuming gluten. The test is crucial for those with IgA deficiency, measuring IgG antibodies against gluten. Key points include:

- Purpose: Diagnose celiac disease, especially in IgA-deficient individuals.
- Procedure: Blood sample analysis after gluten consumption.
- Antibodies Tested: IgG, tTG-IgG, DGP-IgG.
- Interpretation: Positive results suggest gluten reaction; biopsy confirms diagnosis.
- Considerations: IgA deficiency, false positives/negatives.

The test complements other serologic tests, ensuring comprehensive diagnosis and management.

Who Should Get Tested

The Gluten IgE blood test is essential for identifying allergic reactions to gluten, a protein in wheat, barley, and rye. It helps differentiate between gluten-related disorders, such as wheat allergy and celiac disease. Key points include:

- Purpose: Detects IgE antibodies indicating gluten allergy.
- Procedure: Involves a blood draw analyzed via fluorescence enzyme immunoassay.
- Symptoms: Gastrointestinal issues, skin reactions, respiratory symptoms, and systemic reactions like anaphylaxis.
- Diagnostic Process: Initial screening, confirmatory testing, and clinical evaluation.
- Management: Gluten-free diet for confirmed cases.

This test aids in accurate diagnosis and management.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for diagnosing celiac disease. The Gluten IgG test detects gluten-specific IgG antibodies, indicating an immune response to gluten. Here's how to interpret the results:

- Positive Result: Suggests gluten sensitivity; further testing, like a small intestinal biopsy, is recommended for confirmation.
- Negative Result: Doesn't rule out celiac disease, especially if on a gluten-free diet; additional tests may be needed.

Considerations include IgA deficiency, which may necessitate alternative tests like tTG-IgG. Always consult healthcare professionals for comprehensive diagnosis and management.

Price of test:£34

The lowest price from the last 30 days: £34

AI-Powered Insights and Expert Validation

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