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Helicobacter Pylori IgG

Helicobacter Pylori IgG

The Helicobacter pylori IgG test is a serological assay designed to detect IgG antibodies against the bacterium Helicobacter pylori in the blood. This bacterium is a known cause of peptic ulcer disease and chronic gastritis. The test is primarily used to help diagnose H. pylori infection in patients exhibiting gastrointestinal symptoms. A positive result indicates exposure to the bacterium, but it does not confirm an active infection, as antibodies can remain after the infection is cleared. The test employs immunoassay techniques like ELISA and CLIA, requiring a blood sample. While useful, the test has limitations, including low specificity and sensitivity, and potential interference from heterophilic antibodies. It is not recommended as a standalone diagnostic tool. For accurate diagnosis, it should be used alongside other tests, such as the urea breath test or stool antigen assay, to confirm active infection. Proper interpretation of results is essential for effective patient management.

Price of test:£95

The lowest price from the last 30 days: £95

Awaiting result:

12 hours

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Helicobacter pylori IgG test is a serological assay used to detect IgG antibodies against H. pylori in the blood. It aids in diagnosing H. pylori infection, especially in patients with gastrointestinal symptoms. Key points include:

- Purpose: Identifies exposure to H. pylori; positive results indicate antibodies but not necessarily active infection.
- Methodology: Utilizes ELISA or CLIA techniques.
- Specimen: Requires a blood sample; avoid hemolyzed or contaminated sera.
- Interpretation: Positive results need confirmation with other tests like the urea breath test.
- Limitations: Not a front-line diagnostic tool; low specificity and sensitivity.

Who Should Get Tested

The Helicobacter pylori IgG test is crucial for diagnosing H. pylori infections, especially in patients with gastrointestinal symptoms. Key points include:

- Purpose: Detects IgG antibodies against H. pylori, indicating exposure.
- Methodology: Utilizes ELISA or CLIA techniques.
- Specimen: Requires a blood sample, preferably in a serum separator tube.
- Interpretation: Positive results suggest past or active infection; further tests needed for confirmation.
- Limitations: Not a front-line tool due to low specificity; false positives possible.
- Additional Tests: Urea breath test and stool antigen assay confirm active infection.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for accurate diagnosis and treatment. The Helicobacter pylori IgG test detects IgG antibodies against H. pylori, a bacterium linked to peptic ulcers and gastritis. Key points include:

- Positive Result: Indicates exposure to H. pylori; does not confirm active infection.
- Negative Result: Suggests no prior infection.
- Equivocal Result: Requires retesting or alternative methods.
- Limitations: Not a front-line diagnostic tool; low specificity and sensitivity.
- Confirmation: Use additional tests like urea breath test for active infection.

Interpreting results with clinical evaluation ensures appropriate care.

Price of test:£95

The lowest price from the last 30 days: £95

AI-Powered Insights and Expert Validation

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