Hippuric acid

The Hepatitis B e Antibody (anti-HBe) test is an essential diagnostic tool for assessing the infection status of individuals with hepatitis B virus (HBV). This test detects the presence of anti-HBe antibodies, which typically emerge during the recovery phase of acute hepatitis B, indicating reduced viral replication and lower infectivity risk. The primary purpose of the anti-HBe test is to evaluate the stage and prognosis of HBV infection, helping to determine whether the virus is actively replicating or has entered a latent phase. A positive anti-HBe result suggests a transition to a less active infection phase, while its absence, especially alongside the presence of Hepatitis B e Antigen (HBeAg), indicates active viral replication. The test requires a serum or plasma specimen and is performed using competitive chemiluminescence immunoassay (CLIA) or electrochemiluminescence immunoassay (ECLIA). It is crucial for monitoring the serologic response in chronically HBV-infected patients undergoing antiviral therapy, aiding in effective infection management.

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Price of test:£105

The lowest price from the last 30 days: £105

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Awaiting result:

One day

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Collect material:

Urine

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Prepare:

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Purpose of the test

The Hepatitis B e Antibody (anti-HBe) test is vital for assessing hepatitis B infection status. It helps determine the infection stage and prognosis by indicating viral replication levels. Key points include:

- Presence of Anti-HBe: Suggests reduced viral replication and lower infectivity, marking a transition to a less active infection phase.
- Absence of Anti-HBe: Indicates active viral replication and high infectivity, especially if HBeAg is present.
- Clinical Implications: Anti-HBe presence signals recovery and long-term immunity but requires ongoing monitoring in chronic carriers.

Specimen collection involves serum or plasma, with specific storage and rejection criteria.

Who Should Get Tested

The hippuric acid urine test is essential for individuals exposed to aromatic solvents like toluene, benzyl alcohol, and xylene. Key groups who should be tested include:

- Industrial Workers: Those in manufacturing, construction, and chemical processing are at risk due to frequent exposure.
- Environmental Health Professionals: Individuals monitoring contaminated areas may need testing to assess exposure levels.
- Clinical Patients: Those showing symptoms of solvent exposure, such as neurological issues, should be evaluated.

This test helps identify exposure levels, ensuring timely intervention to prevent adverse health effects.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Preparing for Urinalysis Test
Buy container
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Buy sterile, disposable urine containers from pharmacies.

You can also buy a container from a diagnostic centre but the price will be higher. Container is not included in the price of the tests.
Time of day
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Ideally, collect the first urine in the morning after an 8-hour overnight rest or at least 4 hours after the last urination to prevent functional proteinuria.
Mid-stream Sample
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Collect the urine mid-stream, not at the beginning or end of urination, to avoid contamination. The sample volume should be 20 to 100 milliliters, depending on the container's size.
Hygiene
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Wash the area around the urethra with warm water, without using any cleaning or disinfecting products.
Fasting
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Do not eat or drink for 12 hours before collecting the urine sample. If necessary, you can drink one glass of clean, unflavoured water during this time.
Physical activity
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Avoid intense physical activity before providing a urine sample, as it can lead to an increase in protein and ketone levels in urine.
Menstrual period
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Women should avoid providing a urine sample during the menstrual period or within two days of its completion, as this can affect the test results due to the presence of red blood cells and epithelial cells in the urine.
Sexual activity
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Abstain from sexual activity before providing a urine sample.
Deliver sample
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Take the sample(s) to the sampling point on the same day. Storage: Keep the samples at refrigerated temperature (+2...+8°C) until they are taken to the sampling point.
Interpreting Test Results

Understanding test results for the Hepatitis B e Antibody (anti-HBe) test is vital for managing HBV infection. This test helps determine the infection stage and prognosis by assessing viral replication activity.

- Presence of Anti-HBe:
- Indicates reduced viral replication and lower infectivity.
- Suggests transition to a less active infection phase.

- Absence of Anti-HBe:
- Suggests active viral replication and high infectivity.

- Clinical Implications:
- Signals recovery from acute hepatitis B.
- Requires ongoing monitoring in chronic carriers.

This test aids in evaluating treatment efficacy and infection management.

Price of test:£105

The lowest price from the last 30 days: £105

AI-Powered Insights and Expert Validation
Advanced AI Interpretation
Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.
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Language Model and Trusted Sources
At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.
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