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Hepatitis B e Antibody

Hepatitis B e Antibody

The Hepatitis B e Antibody (anti-HBe) test is an essential diagnostic tool for assessing the infection status of individuals with hepatitis B virus (HBV). This test detects the presence of anti-HBe antibodies, which typically emerge during the recovery phase of acute hepatitis B, indicating reduced viral replication and lower infectivity risk. The primary purpose of the anti-HBe test is to evaluate the stage and prognosis of HBV infection, helping to determine whether the virus is actively replicating or has entered a latent phase. A positive anti-HBe result suggests a transition to a less active infection phase, while its absence, especially alongside the presence of Hepatitis B e Antigen (HBeAg), indicates active viral replication. The test requires a serum or plasma specimen and is performed using competitive chemiluminescence immunoassay (CLIA) or electrochemiluminescence immunoassay (ECLIA). It is crucial for monitoring the serologic response in chronically HBV-infected patients undergoing antiviral therapy, aiding in effective infection management.

Price of test:£108

The lowest price from the last 30 days: £108

Awaiting result:

12 hours

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Hepatitis B e Antibody (anti-HBe) test is vital for assessing hepatitis B infection status. It helps determine the infection stage and prognosis by indicating viral replication levels. Key points include:

- Presence of Anti-HBe: Suggests reduced viral replication and lower infectivity, marking a transition to a less active infection phase.
- Absence of Anti-HBe: Indicates active viral replication and high infectivity, especially if HBeAg is present.
- Clinical Implications: Anti-HBe presence signals recovery and long-term immunity but requires ongoing monitoring in chronic carriers.

Specimen collection involves serum or plasma, with specific storage and rejection criteria.

Who Should Get Tested

The Hepatitis B e Antibody (anti-HBe) test is vital for assessing hepatitis B infection status. It helps determine if the virus is actively replicating or in a latent phase. Key points include:

- Presence of Anti-HBe: Indicates reduced viral replication and lower infectivity. However, HBV DNA may still be present.
- Absence of Anti-HBe: Suggests active viral replication and high infectivity.
- Specimen Requirements: Requires 0.5 mL serum/plasma.
- Storage: Room temperature (7 days), refrigerated (14 days), frozen (14 days).
- Methodology: Uses chemiluminescence immunoassay.

This test is crucial for monitoring chronic HBV infection and treatment efficacy.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the Hepatitis B e Antibody (anti-HBe) test is vital for managing HBV infection. This test helps determine the infection stage and prognosis by assessing viral replication activity.

- Presence of Anti-HBe:
- Indicates reduced viral replication and lower infectivity.
- Suggests transition to a less active infection phase.

- Absence of Anti-HBe:
- Suggests active viral replication and high infectivity.

- Clinical Implications:
- Signals recovery from acute hepatitis B.
- Requires ongoing monitoring in chronic carriers.

This test aids in evaluating treatment efficacy and infection management.

Price of test:£108

The lowest price from the last 30 days: £108

AI-Powered Insights and Expert Validation

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