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Helicobacter Pylori IgG

Helicobacter Pylori IgG

The Hepatitis Delta Antibody (anti-HDV) test is an essential diagnostic tool for detecting antibodies against the hepatitis delta virus (HDV) in human serum. HDV requires the presence of hepatitis B virus (HBV) to replicate and can cause severe liver disease, especially in those with chronic HBV infection. This test is crucial for diagnosing HDV in patients with acute or chronic HBV, identifying HDV superinfection, and managing HBV patients, as HDV can worsen the prognosis. Utilizing Enzyme Immunoassay (EIA), the test detects total antibodies (IgG and IgM) against HDV, ensuring high sensitivity and specificity. Blood samples are collected and processed promptly to maintain accuracy. Results are interpreted as negative, positive, or borderline, with positive results indicating coinfection, superinfection, or resolved infection. While highly effective, the test has limitations, such as potential false positives and challenges in immunocompromised patients. Reflex testing for HDV RNA may follow positive results to confirm infection and guide treatment.

Price of test:£83

The lowest price from the last 30 days: £83

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Hepatitis Delta Antibody test is essential for detecting HDV antibodies in patients with HBV. It helps identify:

- Coinfection: Simultaneous HBV and HDV infection.
- Superinfection: HDV infection in chronic HBV patients.
- Resolved Infection: Past HDV exposure.

Methodology involves Enzyme Immunoassay (EIA) for accurate detection. Proper specimen handling is crucial, with serum separated and frozen promptly. Results interpretation includes:

- Negative: No HDV infection.
- Positive: Indicates coinfection, superinfection, or resolved infection.

Limitations include false positives and challenges in immunocompromised patients. Reflex testing with HDV RNA quantification aids in confirming active infection.

Who Should Get Tested

The Helicobacter pylori IgG test is crucial for diagnosing H. pylori infections, especially in patients with gastrointestinal symptoms. Key points include:

- Purpose: Detects IgG antibodies against H. pylori, indicating exposure.
- Methodology: Utilizes ELISA or CLIA techniques.
- Specimen: Requires a blood sample, preferably in a serum separator tube.
- Interpretation: Positive results suggest past or active infection; further tests needed for confirmation.
- Limitations: Not a front-line tool due to low specificity; false positives possible.
- Additional Tests: Urea breath test and stool antigen assay confirm active infection.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for effective patient management. Here's a concise guide:

- Negative Results: Indicate no HDV infection or past exposure. However, early infection or immunocompromised states may yield false negatives.

- Positive Results: Suggests:
- Coinfection with HBV and HDV.
- Superinfection in chronic HBV patients.
- Resolved past infection.

- Borderline Results: Require retesting in 1-2 weeks for clarity.

Consider clinical history and potential false positives due to cross-reactivity. Reflex testing may be necessary for comprehensive assessment.

Price of test:£83

The lowest price from the last 30 days: £83

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