HLA B51

The HLA B51 test is a genetic analysis designed to detect the presence of the HLA B51 allele, a marker linked to autoimmune conditions, particularly Behçet's disease. This chronic disorder is characterized by recurrent ulcers, skin lesions, and eye inflammation. The test is instrumental in diagnosing Behçet's disease, offering genetic insights that aid in disease management and treatment planning. Additionally, it plays a crucial role in organ and tissue transplantation by assessing donor-recipient compatibility, thereby reducing the risk of rejection. The test also evaluates the risk of other autoimmune diseases associated with the HLA B51 allele. It requires blood or buccal swab samples and employs methodologies like PCR and massively parallel sequencing. With a turnaround time of 5 to 7 business days, the test boasts high specificity but should be used alongside other diagnostic tools due to its limitations. A positive result indicates an increased risk for Behçet's disease, guiding clinicians in patient management.

Price of test:£282

The lowest price from the last 30 days: £282

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The HLA B51 test is a genetic analysis used to identify the presence of the HLA B51 allele, linked to autoimmune conditions like Behçet's disease. This test is essential for:

- Diagnosing Behçet's disease by identifying genetic predisposition.
- Assessing organ and tissue transplant compatibility to reduce rejection risk.
- Evaluating autoimmune disease risk associated with the HLA B51 allele.

Sample requirements include blood or buccal swabs. Methods like PCR and SSOP are used, with results in 5-7 days. Despite its utility, the test isn't solely diagnostic and should be used alongside other evaluations.

Who Should Get Tested

The HLA B51 test is essential for identifying individuals at risk for autoimmune diseases, particularly Behçet's disease. It aids in diagnosis and treatment planning by detecting the HLA B51 allele. Key indications include:

- Behçet's Disease Diagnosis: Recommended for suspected cases, as it indicates increased predisposition.
- Organ and Tissue Transplantation: Ensures compatibility, reducing rejection risk.
- Autoimmune Disease Risk Assessment: Evaluates risk for other conditions linked to HLA B51.

The test uses blood or buccal swabs, with results in 5-7 days, offering high specificity and sensitivity.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for informed decision-making. Here's a concise guide:

- Positive Result: Indicates the presence of the HLA B51 allele, suggesting an increased risk for Behçet's disease and potential autoimmune conditions. It aids in early diagnosis and treatment planning.

- Negative Result: Suggests a lower likelihood of Behçet's disease but doesn't rule out other autoimmune disorders.

- Transplant Compatibility: A matching HLA B51 status between donor and recipient reduces rejection risk.

- Consultation: Always discuss results with a healthcare provider for comprehensive interpretation and next steps.

Price of test:£282

The lowest price from the last 30 days: £282

AI-Powered Insights and Expert Validation

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