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Isocyanate TDI IgE

Isocyanate TDI IgE

The Isocyanate TDI IgE test is a vital diagnostic tool designed to detect specific IgE antibodies in individuals suspected of having an allergy to toluene diisocyanate (TDI). Commonly found in industrial environments, TDI can trigger severe respiratory and skin reactions in sensitized individuals. This test is particularly crucial for workers in industries utilizing TDI, such as polyurethane foam production, coatings, and adhesives, as it helps diagnose isocyanate asthma, a form of occupational asthma. Utilizing the Fluorescence Enzyme Immunoassay (FEIA) method, the test offers high sensitivity and specificity in detecting allergen-specific IgE antibodies. A serum sample is required, with results typically available within 1-2 business days. The test results are interpreted based on specific IgE levels, aiding healthcare providers in making informed decisions about patient management. By identifying individuals with TDI allergies, the test plays a significant role in occupational health, helping to prevent severe allergic reactions and improve patient outcomes.

Price of test:£39

The lowest price from the last 30 days: £39

Awaiting result:

12 hours

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Isocyanate TDI IgE test is essential for diagnosing allergies to toluene diisocyanate, commonly found in industrial settings. It identifies specific IgE antibodies, crucial for diagnosing isocyanate asthma, impacting workers' health. Key points include:

- Methodology: Utilizes Fluorescence Enzyme Immunoassay (FEIA) for high sensitivity.
- Specimen Requirements: Serum sample, 0.3 mL minimum.
- Stability: Refrigerated for 14 days, frozen for 90 days.
- Turnaround: 1-2 business days.
- Interpretation: IgE levels indicate allergy likelihood; context is vital.
- Special Considerations: Inhibition tests confirm IgE specificity.

This test aids in managing occupational health, reducing severe reactions.

Who Should Get Tested

The Isocyanate TDI IgE test is essential for diagnosing allergies to toluene diisocyanate, particularly in industrial workers. This test identifies specific IgE antibodies, indicating an immune response to TDI, which is crucial for diagnosing isocyanate asthma. Key points include:

- Clinical Utility: Identifies sensitized individuals, crucial for occupational health.
- Methodology: Uses Fluorescence Enzyme Immunoassay for high sensitivity.
- Specimen Requirements: Serum sample, 0.3 mL minimum.
- Turnaround Time: 1-2 business days.
- Interpretation: IgE levels indicate allergy severity, requiring clinical context.

This test aids in managing isocyanate-related allergies, improving patient outcomes.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for effective diagnosis and management. The Isocyanate TDI IgE test results are interpreted based on specific IgE levels in the serum:

- Class 0: <0.10 kU/L - Negative
- Class 0/1: 0.10-0.34 kU/L - Equivocal
- Class 1: 0.35-0.69 kU/L - Low Positive
- Class 2: 0.70-3.49 kU/L - Moderate Positive
- Class 3: 3.50-17.49 kU/L - High Positive

Detection of IgE antibodies (class 1 or greater) suggests an allergic response to TDI. Results should be interpreted in the clinical context for accurate diagnosis.

Price of test:£39

The lowest price from the last 30 days: £39

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