Kell Status

The Kell antigen status test is an essential diagnostic procedure used to identify the presence of the Kell antigen on red blood cells, which is crucial for assessing the risk of hemolytic disease of the fetus and newborn (HDFN). This condition arises when maternal antibodies target fetal red blood cells expressing the Kell antigen, potentially leading to severe anemia and other complications. The test involves collecting a blood sample, typically in a lavender-top (EDTA) tube, and analyzing it using hemagglutination techniques to determine Kell antigen presence. Results indicate whether an individual is Kell positive, Kell negative, or heterozygous for the antigen. Understanding Kell status is vital in pregnancy management, blood transfusions, and genetic counseling, helping prevent adverse reactions and guide clinical decisions. Despite limitations like false-negative results and specimen quality issues, the test remains a critical tool in transfusion medicine and obstetrics, ensuring better management of red blood cell antigen-related disorders.

Price of test:£193

The lowest price from the last 30 days: £193

Awaiting result:

14 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Kell antigen status test is essential for assessing the risk of alloimmune hemolytic disease in newborns. This condition arises when maternal antibodies attack fetal red blood cells expressing the Kell antigen. The test involves:

- Specimen Collection: Collect 0.5 mL of blood in a lavender-top (EDTA) tube.
- Transportation: Quickly transport to the lab; refrigerate if needed.
- Testing Methodology: Use hemagglutination to detect the Kell antigen.
- Interpretation: Determine if Kell positive, negative, or heterozygous.

Understanding Kell status is crucial in pregnancy, blood transfusions, and genetic counseling.

Who Should Get Tested

The Kell antigen status test is essential for identifying individuals at risk of hemolytic disease of the fetus and newborn (HDFN). Key groups who should be tested include:

- Pregnant Women: Especially those who are Kell negative, to assess the risk of developing antibodies against a Kell-positive fetus.
- Blood Transfusion Recipients: To prevent adverse reactions by ensuring compatibility.
- Genetic Counseling Candidates: Families with a history of HDFN benefit from understanding their Kell status.
- Individuals with Rare Disorders: Those with conditions like McLeod syndrome, linked to Kell antigen expression.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the Kell antigen status test is vital for managing potential health risks. Here's a concise breakdown:

- Kell Positive: Indicates the presence of the K antigen on red blood cells, posing a risk for alloimmune reactions.
- Kell Negative: Absence of the K antigen, reducing the risk of hemolytic disease.
- Heterozygous: Presence of both K and k alleles, indicating partial expression of the K antigen.

These results guide clinical decisions in pregnancy, transfusions, and genetic counseling, ensuring optimal patient care.

Price of test:£193

The lowest price from the last 30 days: £193

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.

Expert Doctor Confirmation

While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.

Language Model and Trusted Sources

At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

FAQ

Answers to Common Questions

What is GetLabTest.com?

How do I get started with GetLabTest.com?

What diseases can GetLabTest.com detect?

How do I prepare for testing with GetLabTest.com?

Can I speak with a doctor about my results?

Is testing with GetLabTest.com covered by insurance?

How long does it take to receive the test results?

Can I access my test results online?

Is my personal information kept confidential?

What if I have questions or concerns about my test results?