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Lactate Dehydrogenase

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The Lactate Dehydrogenase (LDH) Test is a medical test used to measure the level of LDH in blood or other body fluids. LDH is an enzyme found in many body tissues, including the heart, liver, kidneys, muscles, and blood cells. When these tissues are damaged or destroyed by injury or disease, LDH is released into the bloodstream. Therefore, measuring LDH levels can help diagnose and monitor a variety of medical conditions that affect these tissues.

The LDH test is a simple blood test that involves drawing a small sample of blood from a vein in your arm. The sample is then sent to a lab for analysis. The test can also be done on other body fluids such as cerebrospinal fluid (CSF), pleural fluid, and peritoneal fluid.

LDH testing is often used to diagnose and monitor conditions such as heart attack, liver disease, anemia, cancer, and muscle damage. The results of the test can provide valuable information about the extent and severity of tissue damage or disease.

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Lactate Dehydrogenase (LDH) Test is a valuable tool for diagnosing and monitoring a variety of medical conditions. The test measures the level of LDH, an enzyme found in many body tissues, in the blood or other body fluids. LDH is released into the bloodstream when these tissues are damaged or destroyed by injury or disease. Therefore, measuring LDH levels can provide important information about tissue and cell damage.

The LDH test is commonly used to diagnose and monitor conditions that cause cell damage, such as heart attack, liver disease, anemia, cancer, and muscle damage. It may also be used to assess the severity of certain cancers and to monitor patients during treatment. In addition, LDH testing may be used to evaluate abnormal fluid accumulation in the body.

Detecting these conditions early through LDH testing can lead to better outcomes for patients. For example, early detection of cancer can increase the chances of successful treatment and improve survival rates. Similarly, early detection of heart attack or liver disease can allow for prompt intervention and prevent further damage.

On the other hand, not getting tested can have serious consequences. Delayed diagnosis can lead to more advanced conditions that are more difficult to treat. In some cases, untreated conditions can be life-threatening.

In summary:

- The LDH test measures the level of LDH in blood or other body fluids.
- Measuring LDH levels provides information about tissue and cell damage.
- The test is often used to diagnose and monitor diseases that cause cell damage.
- Early detection by LDH testing leads to better patient outcomes.
- Delayed diagnosis can lead to more advanced disease states that are more difficult to treat.
- Untreated conditions can be life threatening.

Who Should Get Tested

The lactate dehydrogenase (LDH) test may be indicated for a variety of people, depending on their medical history and current symptoms. Some examples of people who may need to be tested include

- People with symptoms of heart attack, liver disease, anemia, cancer, or muscle damage
- Patients undergoing cancer treatment to monitor the effectiveness of treatment
- People with abnormal accumulations of fluid in the body
- People with a family history of certain medical conditions that affect LDH levels

LDH testing is not a routine screening test and is usually ordered only when there is a specific medical concern. Your healthcare provider will determine if LDH testing is appropriate for you based on your individual situation.

If you are experiencing symptoms such as chest pain, fatigue, weakness, or unexplained weight loss, talk to your healthcare provider about whether LDH testing may be appropriate. In addition, if you have been diagnosed with a medical condition that affects LDH levels or have a family history of such conditions, discuss the possibility of LDH testing with your healthcare provider.

Lactate dehydrogenase (LDH) testing may be indicated for individuals with specific medical concerns related to tissue and cell damage. If you have questions about whether LDH testing is right for you, talk to your healthcare provider.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Interpreting the results of the lactate dehydrogenase (LDH) test is important for understanding your health. The test measures LDH levels in blood or other body fluids and compares them to reference ranges established by the laboratory. Reference ranges may vary depending on the laboratory and test method used.

- Normal LDH levels in adults typically range from 135 to 225 U/L.
- Elevated LDH levels may indicate tissue or cell damage due to a variety of medical conditions, including heart attack, liver disease, anemia, cancer, and muscle damage.
- The severity of the LDH elevation may indicate the extent of tissue damage or disease.
- LDH levels may also be used to monitor response to treatment for certain medical conditions.

You should be aware that elevated LDH levels do not necessarily indicate a specific medical condition. Additional testing and evaluation by a healthcare provider is needed to determine the underlying cause of elevated LDH levels.

If you have questions about interpreting your LDH test results or what they mean for your health, talk to your healthcare provider. They can help you understand your results in the context of your individual medical history and symptoms.

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