Kell Status

The lamotrigine laboratory test is essential for managing patients with epilepsy and bipolar disorder by measuring the drug's concentration in serum or plasma. This test ensures that lamotrigine levels remain within the therapeutic range, optimizing treatment efficacy while minimizing adverse effects. It also aids in assessing patient compliance and guiding dose adjustments, especially when interactions with other anticonvulsants are a concern. The test requires a serum or plasma sample collected in specific tubes, with careful handling to maintain sample integrity. Quantitative enzyme immunoassay or liquid chromatography-tandem mass spectrometry (LC-MS/MS) are commonly used methodologies, offering precise measurements. The therapeutic range typically spans 2 to 20 μg/mL, though individual factors may necessitate adjustments. Results are generally available within 2 to 5 days, depending on the laboratory. By providing critical insights into lamotrigine levels, this test supports personalized treatment plans, ensuring optimal outcomes for patients with neurological conditions.

Price of test:£167

The lowest price from the last 30 days: £167

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The lamotrigine test is vital for monitoring drug concentration in patients with epilepsy and bipolar disorder. Key objectives include:

- Therapeutic Monitoring: Ensures drug levels are within the effective range to control symptoms without causing adverse effects.
- Compliance Assessment: Evaluates if patients adhere to their medication regimen, crucial for precise dosing.
- Dose Adjustment: Assists in modifying doses, especially when interacting with other anticonvulsants.

Specimen collection requires serum or plasma, with specific handling to maintain accuracy. The test uses advanced methodologies for precise measurement, ensuring optimal patient care.

Who Should Get Tested

The Kell antigen status test is essential for identifying individuals at risk of hemolytic disease of the fetus and newborn (HDFN). Key groups who should be tested include:

- Pregnant Women: Especially those who are Kell negative, to assess the risk of developing antibodies against a Kell-positive fetus.
- Blood Transfusion Recipients: To prevent adverse reactions by ensuring compatibility.
- Genetic Counseling Candidates: Families with a history of HDFN benefit from understanding their Kell status.
- Individuals with Rare Disorders: Those with conditions like McLeod syndrome, linked to Kell antigen expression.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for lamotrigine is crucial for effective treatment management. The test measures serum concentration to ensure therapeutic levels, assess compliance, and guide dose adjustments. Key points include:

- Therapeutic Range: 2 to 20 μg/mL, varying by patient factors.
- Specimen Collection: Serum or plasma, collected before the next dose.
- Methodology: Enzyme immunoassay or LC-MS/MS for precise measurement.
- Turnaround Time: Typically 2 to 5 days.

Interpreting these results helps optimize treatment for epilepsy and bipolar disorder, ensuring safety and efficacy.

Price of test:£167

The lowest price from the last 30 days: £167

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.

Expert Doctor Confirmation

While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.

Language Model and Trusted Sources

At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

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