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Leishmania Ab's

Leishmania Ab's

Leishmania Ab tests are vital diagnostic tools for detecting antibodies against Leishmania parasites in human blood, serum, or plasma. These tests are crucial for diagnosing visceral leishmaniasis, or kala-azar, a severe disease caused by Leishmania parasites like L. donovani, L. chagasi, and L. infantum. Predominantly used in endemic regions such as India, Nepal, Bangladesh, Sudan, and Brazil, these tests enable healthcare providers to identify infected patients promptly, facilitating timely treatment. The tests utilize immunochromatographic strip assays with recombinant proteins, such as K39, to detect IgG antibodies. A positive result is indicated by the presence of both control and test bands on the strip. While highly sensitive and specific, these tests should not be the sole diagnostic criterion. They are particularly useful in clinical settings for rapid diagnosis, monitoring treatment efficacy, and detecting relapse. Proper specimen handling and adherence to storage guidelines are essential for accurate results.

Price of test:£104

The lowest price from the last 30 days: £104

Awaiting result:

7 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

Leishmania Ab tests are vital for diagnosing visceral leishmaniasis by detecting antibodies against Leishmania parasites. Key points include:

- Application: Essential in endemic regions like India, Nepal, and Brazil.
- Methodology: Uses immunochromatographic strip assays with recombinant proteins.
- Interpretation: Positive result shows both control and test bands.
- Specimen Handling: Requires careful blood collection and plasma separation.
- Sensitivity: High sensitivity and specificity, over 90%.
- Limitations: Not sole diagnostic criteria; false results possible.
- Clinical Use: Rapid diagnosis aids in timely treatment.
- Storage: Store kits between 1°C and 30°C.

Who Should Get Tested

Leishmania Ab tests are vital for diagnosing visceral leishmaniasis, a severe disease caused by Leishmania parasites. These tests are crucial in endemic regions like India, Nepal, and Brazil. Key points include:

- Purpose: Aid in diagnosing active visceral leishmaniasis.
- Methodology: Uses immunochromatographic strip assays with recombinant proteins.
- Interpretation: Positive results show both control and test bands.
- Specimen Handling: Proper collection and handling are essential.
- Sensitivity: High sensitivity and specificity in endemic areas.
- Limitations: Not sole diagnostic criteria; false results possible.
- Clinical Use: Rapid diagnosis aids in timely treatment.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for Leishmania Ab tests is crucial for diagnosing visceral leishmaniasis. Here's a concise guide:

- Positive Result: Both control and test bands appear, indicating antibodies against Leishmania.
- Negative Result: Only the control band appears, suggesting no antibodies detected.
- Invalid Result: No bands visible; retest with a new kit.

Ensure proper specimen collection and handling for accuracy. Remember, these tests are highly sensitive and specific but should be part of a comprehensive clinical evaluation.

Price of test:£104

The lowest price from the last 30 days: £104

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

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