The Lp-PLA2 (PLAC) test is a specialized laboratory assessment that measures the activity of the enzyme lipoprotein-associated phospholipase A2 (Lp-PLA2) in the blood. This enzyme is closely linked to atherosclerosis, a condition marked by the accumulation of fatty deposits in the arteries, which can lead to cardiovascular diseases and strokes. Lp-PLA2 is primarily associated with low-density lipoprotein (LDL) particles and plays a role in the oxidative modification of LDL, contributing to plaque formation and destabilization in the arteries. The test involves an enzyme assay using a spectrophotometric method to determine Lp-PLA2 activity, providing a reliable measure of cardiovascular risk. It requires a blood sample, with results reported in nanomoles per minute per milliliter (nmol/min/mL). The Lp-PLA2 test is particularly useful for predicting coronary heart disease risk in patients without prior cardiovascular events, serving as a vascular-specific marker of inflammation.
The Lp-PLA2 (PLAC) test is a specialized laboratory assessment that measures the activity of the enzyme lipoprotein-associated phospholipase A2 (Lp-PLA2) in the blood. This enzyme is closely linked to atherosclerosis, a condition marked by the accumulation of fatty deposits in the arteries, which can lead to cardiovascular diseases and strokes. Lp-PLA2 is primarily associated with low-density lipoprotein (LDL) particles and plays a role in the oxidative modification of LDL, contributing to plaque formation and destabilization in the arteries. The test involves an enzyme assay using a spectrophotometric method to determine Lp-PLA2 activity, providing a reliable measure of cardiovascular risk. It requires a blood sample, with results reported in nanomoles per minute per milliliter (nmol/min/mL). The Lp-PLA2 test is particularly useful for predicting coronary heart disease risk in patients without prior cardiovascular events, serving as a vascular-specific marker of inflammation.
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The Lp-PLA2 test is a crucial tool for assessing cardiovascular risk by measuring the activity of the enzyme linked to atherosclerosis. Key points include:
- Enzyme Role: Lp-PLA2 is involved in LDL oxidation, contributing to plaque formation.
- Test Method: Conducted via spectrophotometry, measuring enzyme activity in blood samples.
- Specimen Handling: Requires careful handling to prevent hemolysis; stable when refrigerated.
- Result Interpretation: Levels above 225 nmol/min/mL indicate higher cardiovascular risk.
- Clinical Use: Helps predict coronary heart disease risk, independent of other factors.
- Patient Prep: No fasting needed; disclose all medications to ensure accuracy.
The Pear IgG test is essential for diagnosing and managing pear-related allergies or sensitivities. It measures IgG antibodies in the serum, indicating an immune response to pear. This test is crucial for:
- Allergy Diagnosis: Identifying if symptoms like skin rashes or respiratory issues are due to pear allergies.
- Immunotherapy Planning: Guiding treatment decisions and monitoring therapy effectiveness.
- Food Intolerance: Providing insights into adverse reactions to pear.
Results must be interpreted with clinical context, considering other diagnostic methods and patient symptoms, to ensure accurate diagnosis and management.
Understanding test results is crucial for assessing cardiovascular risk through the Lp-PLA2 (PLAC) test. This test measures the activity of the enzyme Lp-PLA2, linked to atherosclerosis development. Key points include:
- Result Interpretation: Reported in nmol/min/mL, with a threshold of 225 indicating high cardiovascular risk.
- Clinical Context: Results should be considered alongside other risk factors and clinical evaluations.
- Utility: Useful for predicting coronary heart disease risk, especially in patients without prior cardiovascular events.
- Limitations: Influenced by medications and sample handling; proper procedures are essential for accuracy.
The lowest price from the last 30 days: £34
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