Pear IgG

The Lp-PLA2 (PLAC) test is a specialized laboratory assessment that measures the activity of the enzyme lipoprotein-associated phospholipase A2 (Lp-PLA2) in the blood. This enzyme is closely linked to atherosclerosis, a condition marked by the accumulation of fatty deposits in the arteries, which can lead to cardiovascular diseases and strokes. Lp-PLA2 is primarily associated with low-density lipoprotein (LDL) particles and plays a role in the oxidative modification of LDL, contributing to plaque formation and destabilization in the arteries. The test involves an enzyme assay using a spectrophotometric method to determine Lp-PLA2 activity, providing a reliable measure of cardiovascular risk. It requires a blood sample, with results reported in nanomoles per minute per milliliter (nmol/min/mL). The Lp-PLA2 test is particularly useful for predicting coronary heart disease risk in patients without prior cardiovascular events, serving as a vascular-specific marker of inflammation.

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Price of test:£34

The lowest price from the last 30 days: £34

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Lp-PLA2 test is a crucial tool for assessing cardiovascular risk by measuring the activity of the enzyme linked to atherosclerosis. Key points include:

- Enzyme Role: Lp-PLA2 is involved in LDL oxidation, contributing to plaque formation.
- Test Method: Conducted via spectrophotometry, measuring enzyme activity in blood samples.
- Specimen Handling: Requires careful handling to prevent hemolysis; stable when refrigerated.
- Result Interpretation: Levels above 225 nmol/min/mL indicate higher cardiovascular risk.
- Clinical Use: Helps predict coronary heart disease risk, independent of other factors.
- Patient Prep: No fasting needed; disclose all medications to ensure accuracy.

Who Should Get Tested

The Pear IgG test is essential for diagnosing and managing pear-related allergies or sensitivities. It measures IgG antibodies in the serum, indicating an immune response to pear. This test is crucial for:

- Allergy Diagnosis: Identifying if symptoms like skin rashes or respiratory issues are due to pear allergies.
- Immunotherapy Planning: Guiding treatment decisions and monitoring therapy effectiveness.
- Food Intolerance: Providing insights into adverse reactions to pear.

Results must be interpreted with clinical context, considering other diagnostic methods and patient symptoms, to ensure accurate diagnosis and management.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results is crucial for assessing cardiovascular risk through the Lp-PLA2 (PLAC) test. This test measures the activity of the enzyme Lp-PLA2, linked to atherosclerosis development. Key points include:

- Result Interpretation: Reported in nmol/min/mL, with a threshold of 225 indicating high cardiovascular risk.
- Clinical Context: Results should be considered alongside other risk factors and clinical evaluations.
- Utility: Useful for predicting coronary heart disease risk, especially in patients without prior cardiovascular events.
- Limitations: Influenced by medications and sample handling; proper procedures are essential for accuracy.

Price of test:£34

The lowest price from the last 30 days: £34

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Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.
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At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.
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