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Maple tree IgG

Maple tree IgG

The methylmalonic acid (MMA) urine test is a vital diagnostic tool used to evaluate methylmalonic acid levels in urine, primarily for diagnosing vitamin B12 deficiency and certain inherited metabolic disorders, such as methylmalonic acidurias. Elevated MMA levels suggest a vitamin B12 deficiency, as this vitamin is crucial for converting methylmalonyl-CoA to succinyl-CoA in metabolism. The test involves collecting a urine sample, either randomly or over 24 hours, and analyzing it using advanced techniques like liquid chromatography/tandem mass spectrometry (LC/MS-MS) or gas chromatography-mass spectrometry (GC-MS). These methods ensure precise MMA quantification. Results are compared to reference ranges, with elevated levels indicating potential vitamin B12 deficiency or methylmalonic acidemia. Clinically, the test aids in diagnosing B12 deficiency, monitoring methylmalonic acidemia, and is part of newborn screening programs. Patients typically fast before the test to ensure accuracy. Despite not being FDA-approved, the test is performed in CLIA-certified labs, ensuring reliability.

Price of test:£34

The lowest price from the last 30 days: £34

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The methylmalonic acid (MMA) urine test is a diagnostic tool for assessing vitamin B12 deficiency and certain metabolic disorders. Key points include:

- Purpose: Measures MMA levels to diagnose vitamin B12 deficiency and methylmalonic acidurias.
- Procedure: Involves collecting a urine sample, either random or 24-hour, and analyzing it using LC/MS-MS or GC-MS.
- Specimen Requirements: Minimum 5 mL urine, stored appropriately.
- Interpretation: Elevated MMA suggests vitamin B12 deficiency or metabolic disorder.
- Clinical Applications: Diagnoses vitamin B12 deficiency, methylmalonic acidemia, and used in newborn screening.

Who Should Get Tested

The Maple tree IgG test is a diagnostic tool used to identify IgG antibodies against maple tree pollen, aiding in the understanding of non-allergic sensitivities. This test is crucial for diagnosing conditions that mimic allergic reactions but don't involve typical allergic mechanisms. The procedure involves:

- Collecting a blood sample.
- Centrifuging to separate serum.
- Aliquoting serum for testing.
- Conducting an enzyme immunoassay (EIA).

Results are reported in mcg/mL, with interpretations guiding diagnosis and management. Despite varying clinical utility, this test is valuable for specific non-allergic sensitivity cases.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for effective diagnosis and treatment. The methylmalonic acid (MMA) urine test measures MMA levels to assess vitamin B12 deficiency and certain metabolic disorders. Here's a brief overview:

- Elevated MMA Levels: Suggest vitamin B12 deficiency or methylmalonic acidemia.
- Normal Ranges: Typically up to 4.0 mmol/mol creatinine in urine.
- Interpretation: Results are compared to reference ranges and considered alongside other tests like homocysteine levels.
- Clinical Applications: Useful for diagnosing B12 deficiency, monitoring methylmalonic acidemia, and newborn screening.

Understanding these results aids in accurate diagnosis and effective treatment planning.

Price of test:£34

The lowest price from the last 30 days: £34

AI-Powered Insights and Expert Validation

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At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

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