Onion IgE

The Onion IgE test is a specialized diagnostic tool designed to identify allergic reactions to onions by detecting specific IgE antibodies in the serum. Utilizing Fluorescence Enzyme Immunoassay (FEIA) methodology, the test involves collecting a blood sample, preparing the onion allergen on an ImmunoCAP, and measuring the fluorescence produced by the reaction of IgE antibodies with the allergen. The fluorescence intensity correlates with the severity of the allergy, providing results expressed in kU/L. These results help in diagnosing onion allergies, confirming sensitization, and guiding treatment decisions, such as immunotherapy. The test is clinically significant as it aids in understanding the immune response and managing allergic conditions effectively. Typically performed Monday through Friday, the Onion IgE test offers results within 1 to 3 days. Cleared by the FDA and verified by the Mayo Clinic, this test is a reliable tool for healthcare providers in diagnosing and managing onion allergies.

Price of test:£39

The lowest price from the last 30 days: £39

Awaiting result:

12 hours

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Onion IgE test is a diagnostic tool for identifying onion allergies by detecting specific IgE antibodies in the serum. Its primary purpose is to diagnose onion allergies and identify allergens linked to allergic reactions and anaphylaxis. The test uses Fluorescence Enzyme Immunoassay (FEIA) and involves:

- Specimen Collection: Blood sample collection and serum separation.
- Allergen Preparation: Onion allergen coupled to ImmunoCAP.
- Reaction and Measurement: IgE antibodies react with the allergen, producing fluorescence.

Results are interpreted based on fluorescence values, indicating allergy severity. This test aids in diagnosis and treatment decisions, ensuring effective allergy management.

Who Should Get Tested

The Onion IgE test is essential for diagnosing onion allergies by detecting specific IgE antibodies in the serum. It is particularly useful for:

- Identifying allergens causing allergic reactions.
- Confirming sensitization before immunotherapy.
- Investigating allergic reactions to various allergens.

The test uses Fluorescence Enzyme Immunoassay (FEIA) methodology, involving:

- Blood sample collection.
- Allergen preparation with ImmunoCAP.
- Reaction and measurement of IgE levels.

Results are interpreted based on fluorescence values, indicating allergy severity. This test aids in managing allergies effectively, guiding treatment decisions, and ensuring accurate diagnosis.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for managing onion allergies effectively. The Onion IgE test measures specific IgE antibodies in the serum, indicating an immune response to onions. Results are expressed in kU/L, with interpretations as follows:

- Negative: <0.10 kU/L
- Borderline: 0.10-0.34 kU/L
- Equivocal: 0.35-0.69 kU/L
- Positive: 0.70-3.49 kU/L
- Strongly Positive: 3.50-17.4 kU/L
- Very Strongly Positive: 17.5-49.9 kU/L
- Extremely Strongly Positive: 50.0-99.9 kU/L
- Extremely High: ≥100 kU/L

Higher levels suggest a greater likelihood of allergic disease, guiding treatment decisions and management strategies.

Price of test:£39

The lowest price from the last 30 days: £39

AI-Powered Insights and Expert Validation

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