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Ovarian Antibodies

Ovarian Antibodies

The ovarian antibodies test is a diagnostic procedure designed to detect autoantibodies targeting ovarian tissues, which can signal autoimmune disorders affecting the endocrine system, such as premature ovarian failure (POF) and Addison's disease. Conducted on serum samples, the test employs methodologies like enzyme-linked immunosorbent assay (ELISA) and indirect fluorescent antibody (IFA) to identify these antibodies. ELISA quantifies anti-ovary antibodies using a colorimetric reaction, while IFA uses fluorescently labeled antibodies to visualize antibody presence. Results are categorized as positive, weak positive, or negative, and must be interpreted alongside clinical symptoms and history for accurate diagnosis. Although the test is valuable for diagnosing and monitoring autoimmune endocrinopathies, its specificity and sensitivity can vary, necessitating complementary diagnostic methods. Typically requiring a serum sample, the test results are available within 7 to 14 days. The ovarian antibodies test is instrumental in diagnosing conditions like POF and Addison’s disease, offering critical insights into autoimmune activity affecting the ovaries.

Price of test:£166

The lowest price from the last 30 days: £166

Awaiting result:

2 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The ovarian antibodies test is a diagnostic tool for detecting autoantibodies against ovarian tissues, aiding in diagnosing autoimmune conditions like premature ovarian failure and Addison's disease. It uses methodologies such as:

- ELISA: Quantifies anti-ovary antibodies using enzyme immunoassay.
- IFA: Detects antibodies with fluorescent labeling.

Results are interpreted as positive, weak positive, or negative, and should be considered alongside clinical data. The test is useful for diagnosing and monitoring autoimmune endocrinopathies, requiring a serum sample with a turnaround time of 7-14 days.

Who Should Get Tested

The ovarian antibodies test is essential for diagnosing autoimmune conditions affecting the ovaries. It helps identify:

- Premature Ovarian Failure (POF): Ovaries stop functioning before age 40.
- Addison's Disease: Affects adrenal glands.

Methodologies:

- ELISA: Quantifies antibodies using enzyme immunoassay.
- IFA: Detects antibodies with fluorescent labeling.

Results Interpretation:

- Positive results suggest autoimmune conditions but require clinical correlation.

Clinical Utility:

- Useful for diagnosing and monitoring autoimmune endocrinopathies.

Proper sample collection and storage are crucial for accurate results.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for making informed healthcare decisions. The ovarian antibodies test helps identify autoimmune disorders targeting the ovaries, such as premature ovarian failure and Addison's disease. Here's a brief overview:

- Positive Result: Indicates presence of autoantibodies; suggests potential autoimmune conditions.
- Weak Positive: May require further investigation.
- Negative Result: Typically rules out ovarian-targeted autoimmunity.

Remember, results should be interpreted alongside clinical symptoms and history for accurate diagnosis. Always consult healthcare professionals for comprehensive evaluation and guidance.

Price of test:£166

The lowest price from the last 30 days: £166

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