Plaice IgE

The Plaice IgE blood test detects specific Immunoglobulin E (IgE) antibodies directed against plaice fish proteins, helping to diagnose an allergic reaction to plaice, a flatfish commonly consumed in many diets. The test is used when an individual experiences allergic symptoms after eating plaice or food products containing it.

Typical symptoms of plaice allergy include hives, itching, swelling, gastrointestinal issues, respiratory difficulties, and in severe cases, anaphylaxis. The test is performed using ImmunoCAP® or similar fluorescence enzyme immunoassay techniques. Results are reported in classes from 0 to 6, reflecting the degree of sensitization.

A positive test indicates sensitization but must be interpreted in the context of clinical symptoms. Cross-reactivity with other fish species is possible, but some individuals may be specifically allergic to plaice.

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Price of test:£39

The lowest price from the last 30 days: £39

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Awaiting result:

12 hours

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Collect material:

Blood

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Prepare:

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Purpose of the test

This test is used to:

Confirm sensitization to plaice in individuals with suspected fish allergy

Diagnose allergic reactions to plaice involving IgE-mediated mechanisms

Guide dietary recommendations and allergy management plans

Support differential diagnosis in patients allergic to multiple fish species

Who Should Get Tested

The Plaice IgE test is recommended for:

Individuals who experience allergic symptoms after consuming plaice or fish-based dishes

Patients with known fish allergies who require detailed allergen profiling

Children or adults being evaluated for food allergies

Those with suspected cross-reactivity to fish proteins

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Class 0 (<0.35 kU/L): Negative – no sensitization

Class 1–6 (≥0.35 kU/L and higher): Positive – sensitization to plaice present

Higher classes suggest greater likelihood of clinical allergy

Must be interpreted alongside history of symptoms and, if needed, oral food challenge

Cross-reactivity with other fish is possible, but not guaranteed

Price of test:£39

The lowest price from the last 30 days: £39

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