The pregnenolone test is a vital laboratory examination that measures pregnenolone levels in the blood or serum, offering insights into hormonal balance and potential underlying conditions. Pregnenolone is a precursor hormone essential for synthesizing steroid hormones like progesterone, estrogen, testosterone, and cortisol, which are crucial for overall health. The primary purpose of this test is to aid in diagnosing and managing congenital adrenal hyperplasia (CAH), a disorder marked by enzyme deficiencies affecting hormone conversion. Elevated pregnenolone levels can indicate enzyme dysfunction, leading to hormonal imbalances such as cortisol deficiency and excess androgens, manifesting in symptoms like high blood pressure, ambiguous genitalia in infants, and delayed puberty in adolescents. The test employs liquid chromatography/tandem mass spectrometry (LC/MS-MS) for precise measurement. Specimen collection involves serum or plasma, with immediate freezing to ensure accuracy. The test typically has a 7-10 business day turnaround, providing crucial data for diagnosing CAH and guiding treatment decisions.
The pregnenolone test is a vital laboratory examination that measures pregnenolone levels in the blood or serum, offering insights into hormonal balance and potential underlying conditions. Pregnenolone is a precursor hormone essential for synthesizing steroid hormones like progesterone, estrogen, testosterone, and cortisol, which are crucial for overall health. The primary purpose of this test is to aid in diagnosing and managing congenital adrenal hyperplasia (CAH), a disorder marked by enzyme deficiencies affecting hormone conversion. Elevated pregnenolone levels can indicate enzyme dysfunction, leading to hormonal imbalances such as cortisol deficiency and excess androgens, manifesting in symptoms like high blood pressure, ambiguous genitalia in infants, and delayed puberty in adolescents. The test employs liquid chromatography/tandem mass spectrometry (LC/MS-MS) for precise measurement. Specimen collection involves serum or plasma, with immediate freezing to ensure accuracy. The test typically has a 7-10 business day turnaround, providing crucial data for diagnosing CAH and guiding treatment decisions.
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The pregnenolone test is essential for assessing hormonal balance and diagnosing conditions like congenital adrenal hyperplasia (CAH). It measures pregnenolone levels in the blood, offering insights into enzyme deficiencies affecting steroid hormone synthesis. Key points include:
- Purpose: Diagnoses CAH by identifying enzyme deficiencies.
- Symptoms: High levels linked to high blood pressure, acne, and delayed puberty.
- Procedure: Blood sample collected, serum preferred, frozen for accuracy.
- Methodology: Uses LC/MS-MS for precise measurement.
- Reference Values: Vary by age and sex, crucial for interpretation.
This test aids in identifying hormonal imbalances, guiding effective treatment.
The Pine Nut IgE Blood Test is essential for diagnosing pine nut allergies, identifying allergens responsible for reactions. It measures IgE antibodies using Fluorescence Enzyme Immunoassay (FEIA). Key steps include:
- Sample Collection: Blood is drawn, serum prepared.
- Testing Process: Serum reacts with pine nut allergen on ImmunoCAP.
- Enzyme-Labeled Anti-IgE: Binds to specific IgE.
- Incubation and Washing: Complex forms, unbound elements removed.
- Developing Agent: Causes color change.
- Fluorescence Measurement: Indicates IgE levels.
Results guide treatment, crucial for managing allergic reactions.
Understanding test results for pregnenolone is essential for diagnosing and managing hormonal imbalances. Elevated pregnenolone levels can indicate enzyme deficiencies, such as in congenital adrenal hyperplasia (CAH), leading to hormonal imbalances. Key points to consider:
- Elevated Levels: May suggest CAH or other enzyme deficiencies.
- Symptoms: Acne, oily skin, delayed puberty, high blood pressure.
- Low Levels: Can cause fatigue, mood swings, and irregular cycles.
- Reference Values: Vary by age and sex; adults typically 33-248 ng/dL.
- Clinical Significance: Guides diagnosis and treatment decisions.
The lowest price from the last 30 days: £34
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