Main page
Tests catalogue
Procollagen 1 Pept (N-Terminal)

Procollagen 1 Pept (N-Terminal)

The Procollagen 1 N-Terminal Peptide (P1NP) test is a specialized laboratory assay designed to measure the levels of P1NP in the serum, a key marker of bone formation. P1NP is derived from procollagen type 1, the primary collagen in mineralized bone, and its presence in the bloodstream reflects the rate of new bone synthesis. This test is particularly valuable for monitoring the effectiveness of osteoporosis treatments, such as anabolic therapies that enhance bone density. By assessing changes in P1NP levels, healthcare providers can evaluate the response to treatments like teriparatide, which typically increases P1NP, or bisphosphonates, which decrease it. The test employs a quantitative radioimmunoassay technique, requiring serum samples collected in red-top tubes. Interpretation of results considers age and gender-specific reference ranges, with significant changes indicating therapeutic response. While highly useful, the P1NP test is not suitable for general osteoporosis screening due to individual variability in bone turnover markers.

Price of test:£401

The lowest price from the last 30 days: £401

Awaiting result:

7 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Procollagen 1 N-Terminal Peptide (P1NP) test is crucial for evaluating bone formation. It measures serum levels of P1NP, a marker derived from procollagen type 1, indicating bone synthesis rates. Key objectives include:

- Monitoring Treatment: Assesses response to osteoporosis therapies, like teriparatide, which increases P1NP levels.
- Evaluating Bone Turnover: Differentiates effects of anabolic versus antiresorptive treatments.
- Clinical Utility: Guides therapeutic decisions by reflecting changes in bone density.

Understanding P1NP levels aids in optimizing osteoporosis management and treatment efficacy.

Who Should Get Tested

The Procollagen 1 N-Terminal Peptide (P1NP) test is essential for evaluating bone formation. It is particularly useful for:

- Monitoring Osteoporosis Treatments:
- Teriparatide therapy increases P1NP levels, indicating enhanced bone formation.
- Bisphosphonates decrease P1NP levels, reflecting reduced bone resorption.

- Specimen Handling:
- Serum samples are collected in red-top tubes.
- Consistent collection times minimize diurnal variation.

- Interpreting Results:
- Reference ranges vary by age and gender.
- A ≥21% change from baseline indicates treatment response.

The P1NP test is crucial for managing osteoporosis but not for general screening.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the Procollagen 1 N-Terminal Peptide (P1NP) test involves recognizing its role in assessing bone formation. Key points include:

- Reference Ranges: Vary by age and gender; essential for interpreting results.
- Treatment Monitoring: A ≥21% change from baseline indicates a therapeutic response.
- Treatment Type:
- Bisphosphonates: Expect decreased P1NP levels.
- Teriparatide: Expect increased P1NP levels.
- Limitations: Not suitable for general osteoporosis screening; variability in results.

Understanding these aspects ensures effective use of the P1NP test in clinical practice.

Price of test:£401

The lowest price from the last 30 days: £401

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.

Expert Doctor Confirmation

While our AI provides deep analytical insights, the human touch remains indispensable. Every AI-generated interpretation is meticulously reviewed by experienced medical professionals, ensuring a harmonious blend of advanced technology and expert clinical judgment. This dual-layer approach guarantees that the insights provided are not only technologically sophisticated but also clinically relevant. Our medical experts ensure that the AI's interpretations align with current medical standards and practices, adding a layer of validation that only seasoned healthcare professionals can provide. This process reinforces the reliability of the test results, offering peace of mind to both patients and healthcare providers.

Language Model and Trusted Sources

At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

FAQ

Answers to Common Questions

What is GetLabTest.com?

How do I get started with GetLabTest.com?

What diseases can GetLabTest.com detect?

How do I prepare for testing with GetLabTest.com?

Can I speak with a doctor about my results?

Is testing with GetLabTest.com covered by insurance?

How long does it take to receive the test results?

Can I access my test results online?

Is my personal information kept confidential?

What if I have questions or concerns about my test results?