Red Cell Folate


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Folate is involved in normal red cell maturation and used for the evaluation of macrocytic/megaloblastic anemia. Folate red blood cell (RBC) measurements are used in identification of dietary folate deficiency that might be otherwise difficult to ascertain since serum folate concentration may rapidly rise to normal level after just one balanced meal whereas RBC folate increases more slowly. RBC folate is usually not decreased as a consequence of iron deficiency and the evaluations of individuals with low serum folate and iron levels.

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Purpose of the test

The immunoglobulins blood test measures the amount of immunoglobulins, also known as antibodies, in the blood. These antibodies are proteins produced by the immune system to combat germs, such as viruses and bacteria. The test typically evaluates three primary types of immunoglobulins: IgM, IgG, and IgA. Each of these antibodies plays a unique role in protecting the body from infections. The test aids in diagnosing various health conditions that might affect the immune system.

Who Should Get Tested

Individuals who frequently fall sick with infections or diarrhea might require an immunoglobulins blood test. The test is also used to diagnose and monitor conditions that can cause abnormal levels of IgM, IgG, or IgA, such as autoimmune disorders, certain cancers, chronic infections, and genetic diseases. Additionally, if someone has symptoms suggesting low immunoglobulin levels, such as recurrent infections, they may need this test. It's also relevant for those with a family history of immunodeficiency or if there's suspicion of an issue with immunoglobulin production.

Blood Test Preparation Guidelines
Time of day
It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
Drinking water prior to testing can help with sample collection.
Other factors
Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

The results of the immunoglobulins test will compare the levels of IgM, IgG, and IgA in the blood. Abnormal levels can indicate various conditions, and the interpretation depends on which immunoglobulins are high or low. Low levels might be due to conditions reducing protein in the body, complications from diseases like diabetes, or genetic disorders. High levels could be indicative of autoimmune diseases, hepatitis, chronic infections, or certain cancers. It's essential to note that the immunoglobulins blood test alone cannot diagnose conditions. If results are abnormal, further testing might be required to determine the cause.

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