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Rheumatoid Factor

Rheumatoid Factor

The rheumatoid factor (RF) test is a blood test used to measure the levels of rheumatoid factor, an antibody often present in individuals with autoimmune diseases like rheumatoid arthritis (RA). This test is crucial for diagnosing and managing RA, as well as distinguishing it from other autoimmune conditions such as Sjögren syndrome and lupus. The RF test involves drawing a blood sample, which is then analyzed in a laboratory. No specific preparations are needed, but informing the healthcare provider about any medications or conditions is essential. The test measures antibodies that attack the body's tissues, leading to inflammation and joint damage. Normal RF levels are typically below 15 IU/mL, but this can vary. A positive result suggests autoimmune activity but must be interpreted alongside other tests like anti-CCP and ANA. While not specific to RA, the RF test is a valuable tool in early diagnosis and management, helping prevent long-term joint damage.

Price of test:£41

The lowest price from the last 30 days: £41

Awaiting result:

12 hours

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The rheumatoid factor (RF) test is a crucial diagnostic tool for autoimmune diseases, especially rheumatoid arthritis (RA). It measures RF levels in the blood, aiding in diagnosis and management. Key points include:

- Purpose: Diagnoses RA, differentiates from other autoimmune diseases.
- Procedure: Blood sample drawn, analyzed using methods like latex immunoturbidimetry.
- Preparation: No specific prep, but disclose medications and conditions.
- Results: Normal RF <15 IU/mL; positive results suggest autoimmune activity.
- Interpretation: Positive RF requires further tests for accurate diagnosis.
- Limitations: Not specific to RA; positive in other conditions and some healthy individuals.

Who Should Get Tested

The rheumatoid factor (RF) test is essential for diagnosing autoimmune diseases, especially rheumatoid arthritis (RA). It measures RF levels in the blood, aiding in differentiating RA from other conditions. Here's who should consider testing:

- Individuals with Joint Pain: Persistent joint inflammation or pain may warrant an RF test.
- Suspected Autoimmune Disorders: Symptoms like dry eyes or mouth could indicate Sjögren syndrome or lupus.
- Family History: A family history of RA or autoimmune diseases increases the need for testing.
- Chronic Infections: Conditions like hepatitis C might elevate RF levels.
- Unexplained Symptoms: Unusual fatigue or systemic symptoms may require further investigation.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for managing autoimmune conditions like rheumatoid arthritis (RA). The rheumatoid factor (RF) test measures antibodies in the blood, aiding in the diagnosis of RA and other autoimmune diseases. Here's a quick guide:

- Normal Results: Typically less than 15 IU/mL, but this can vary.
- Positive Results: May indicate RA, Sjögren syndrome, or other conditions, but not definitive on its own.
- Additional Tests: Often paired with anti-CCP, ANA, CRP, and ESR tests for comprehensive diagnosis.
- Limitations: RF can be elevated in other conditions or even in healthy individuals.

Price of test:£41

The lowest price from the last 30 days: £41

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