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Smooth Muscle Abs

Smooth Muscle Abs

The anti-smooth muscle antibody (ASMA) test is a vital blood test used to detect autoantibodies targeting smooth muscle cells, primarily in the liver. This test is essential for diagnosing and managing liver conditions, particularly autoimmune hepatitis (AIH). During the test, a blood sample is collected and analyzed for autoantibodies against smooth muscle antigens using indirect immunofluorescence. The presence of these antibodies, often IgG or IgM, causes fluorescence under a microscope, indicating a positive result. The ASMA test is primarily indicated for patients showing signs of liver diseases like AIH, primary biliary cirrhosis, and cirrhosis. While a positive result suggests the presence of autoantibodies, it does not exclusively confirm AIH, as these antibodies can also appear in conditions like infectious mononucleosis. Preparation for the test is minimal, and risks are low, including minor bleeding or infection. A positive ASMA test aids in diagnosing AIH, guiding treatment with immunosuppressive medications.

Price of test:£68

The lowest price from the last 30 days: £68

Awaiting result:

5 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The ASMA test is a blood test used to detect autoantibodies targeting smooth muscle cells, crucial for diagnosing liver conditions like autoimmune hepatitis (AIH). It involves:

- Collecting a blood sample.
- Analyzing for IgG or IgM autoantibodies.
- Using indirect immunofluorescence.

Indications include:

- Autoimmune hepatitis.
- Primary biliary cirrhosis.
- Distinguishing from systemic lupus erythematosus.

Preparation is minimal, with no dietary restrictions. A positive result suggests:

- Autoimmune hepatitis.
- Possible cirrhosis or infectious mononucleosis.

Risks are minor, including:

- Bleeding.
- Fainting.
- Hematoma.

Treatment involves immunosuppressive medications.

Who Should Get Tested

The ASMA test is essential for diagnosing liver conditions, particularly autoimmune hepatitis. It detects autoantibodies targeting smooth muscle cells. Indications for testing include:

- Autoimmune hepatitis
- Primary biliary cirrhosis
- Cirrhosis

A positive result suggests the presence of these autoantibodies, often linked to autoimmune hepatitis. However, they can also appear in conditions like infectious mononucleosis. Normal results show no antibodies, but a negative test doesn't rule out disease. Risks are minimal, including:

- Bleeding
- Fainting
- Hematoma

Treatment involves immunosuppressive medications to manage autoimmune hepatitis effectively.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is essential for effective diagnosis and management. The ASMA test detects autoantibodies against smooth muscle cells, primarily aiding in diagnosing autoimmune hepatitis. Here's what you need to know:

- Positive Result: Indicates presence of autoantibodies, often linked to autoimmune hepatitis, but can also appear in other conditions.
- Negative Result: Suggests absence of significant autoantibodies, yet doesn't completely rule out autoimmune hepatitis.
- Associated Conditions: Chronic active autoimmune hepatitis, cirrhosis, and infectious mononucleosis.
- Risks: Minimal, including bleeding, fainting, hematoma, and infection.

Understanding these results helps guide appropriate treatment and management strategies.

Price of test:£68

The lowest price from the last 30 days: £68

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