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The Strongyloides antibody test is a serological assay used to detect IgG antibodies against *Strongyloides stercoralis*, the parasite causing strongyloidiasis. This test is vital for diagnosing infections, especially in tropical and subtropical regions and rural southeastern U.S. It is particularly useful for patients with immunocompromised conditions or symptoms like epigastric pain, diarrhea, nausea, and vomiting. The test uses the ELISA method, involving antigen-coated wells and serum samples to detect antibodies. A positive result indicates a current or past infection, but false positives can occur due to other helminth infections. Negative results may require retesting if clinical suspicion remains. The test is not suitable for monitoring therapy response, as antibodies may persist post-infection. Interpretation should consider clinical history and other findings. The test is performed daily, with results available in 1 to 4 days, and requires a serum sample stored at refrigerated temperatures.
The Strongyloides antibody test is a serological assay used to detect IgG antibodies against *Strongyloides stercoralis*, the parasite causing strongyloidiasis. This test is vital for diagnosing infections, especially in tropical and subtropical regions and rural southeastern U.S. It is particularly useful for patients with immunocompromised conditions or symptoms like epigastric pain, diarrhea, nausea, and vomiting. The test uses the ELISA method, involving antigen-coated wells and serum samples to detect antibodies. A positive result indicates a current or past infection, but false positives can occur due to other helminth infections. Negative results may require retesting if clinical suspicion remains. The test is not suitable for monitoring therapy response, as antibodies may persist post-infection. Interpretation should consider clinical history and other findings. The test is performed daily, with results available in 1 to 4 days, and requires a serum sample stored at refrigerated temperatures.
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The Strongyloides antibody test is a serological assay for detecting IgG antibodies against *Strongyloides stercoralis*. It is vital for diagnosing strongyloidiasis, especially in tropical regions and parts of the southeastern U.S. Key points include:
- Purpose: Screens for IgG antibodies to identify past or current infections.
- Methodology: Utilizes ELISA with antigen-coated wells and enzyme-labeled antibodies.
- Specimen: Requires 0.5 mL serum, stored refrigerated.
- Interpretation: Positive indicates infection; false positives possible with other helminths.
- Limitations: Not for therapy monitoring; false negatives possible in acute infections.
IgG antibody testing is essential for diagnosing and monitoring various health conditions. Key groups who may need testing include:
- Infection Diagnosis: Individuals with suspected past or current infections, such as COVID-19 or influenza, can benefit from IgG testing to confirm exposure.
- Immune Deficiency Disorders: Those with low IgG levels may have conditions like X-linked agammaglobulinemia, indicating a need for further evaluation.
- Autoimmune Diseases: Elevated IgG levels can suggest autoimmune diseases like lupus or rheumatoid arthritis.
- Monoclonal Gammopathies: Patients with conditions like multiple myeloma may show abnormal IgG production.
- Food Sensitivities: Testing can identify IgG antibodies against foods, indicating potential sensitivities.
Understanding test results for the Strongyloides antibody test is crucial for accurate diagnosis and management. Here's a brief guide:
- Positive Result: Indicates current or past infection with *S. stercoralis*. However, false positives may occur due to other helminth infections. Clinical correlation is essential.
- Negative Result: Suggests no detectable IgG antibodies. If clinical suspicion remains high, consider retesting in 10-14 days.
- Clinical Correlation: Always interpret results alongside clinical history and other tests. A single negative result doesn't rule out infection.
- Limitations: Be aware of potential false positives and negatives. The test isn't suitable for monitoring therapy response.
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