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Thyroid Receptor Antibodies

Thyroid Receptor Antibodies

The Thyroid Receptor Antibody (TRAb) test is an essential diagnostic tool for detecting and managing autoimmune thyroid diseases, particularly Graves' disease and Hashimoto's disease. It measures autoantibodies targeting the thyroid-stimulating hormone receptor (TSHR), which can disrupt normal thyroid function. The TRAb test is crucial for differentiating causes of thyrotoxicosis, diagnosing Graves' disease, and assessing neonatal thyrotoxicosis risk in pregnant women with a history of Graves' disease. It is especially useful when clinical presentations are ambiguous or when other diagnostic methods are unsuitable. The test employs a quantitative electrochemiluminescent immunoassay (ECLIA) to detect TRAb levels, offering high sensitivity and specificity. Clinically, it aids in therapy selection, prognostic predictions for Graves' ophthalmopathy and pretibial myxedema, and risk prediction for fetal and neonatal thyrotoxicosis. Proper specimen handling and storage are vital for accurate results, with frozen specimens preferred for long-term storage. Overall, the TRAb test is invaluable in personalized patient care for autoimmune thyroid conditions.

Price of test:£180

The lowest price from the last 30 days: £180

Awaiting result:

5 days

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The TRAb test is vital for diagnosing and managing autoimmune thyroid diseases. It measures autoantibodies targeting the TSH receptor, aiding in:

- Differential Diagnosis: Helps distinguish causes of thyrotoxicosis, such as Graves' disease.
- Graves' Disease Diagnosis: Elevated TRAb levels indicate this condition.
- Neonatal Risk Assessment: Evaluates risk of neonatal thyrotoxicosis in pregnant women with Graves' history.
- Gestational Thyrotoxicosis: Differentiates it from Graves' disease.

Performed via electrochemiluminescent immunoassay, it offers high sensitivity and specificity, guiding therapy and prognosis.

Who Should Get Tested

The Thyroid Receptor Antibody (TRAb) test is vital for diagnosing autoimmune thyroid diseases like Graves' and Hashimoto's. It measures autoantibodies targeting the thyroid-stimulating hormone receptor, affecting thyroid function. Key uses include:

- Differential Diagnosis of Thyrotoxicosis: Helps distinguish causes like Graves' disease.
- Diagnosing Graves' Disease: Elevated TRAb levels indicate this condition.
- Neonatal Thyrotoxicosis Risk: Assesses risk in pregnant women with Graves' history.
- Gestational Thyrotoxicosis: Differentiates from Graves' disease.

The test's sensitivity and specificity aid in therapy selection and prognostic predictions, enhancing patient care.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for effective management of autoimmune thyroid diseases. The Thyroid Receptor Antibody (TRAb) test provides valuable insights:

- Differential Diagnosis: Helps distinguish between causes of thyrotoxicosis, such as Graves' disease and gestational thyrotoxicosis.
- Graves' Disease Diagnosis: Elevated TRAb levels indicate Graves' disease, even with normal thyroid function tests.
- Neonatal Risk Assessment: In pregnant women, high TRAb levels suggest a risk of neonatal thyrotoxicosis.
- Therapy and Prognosis: Guides treatment decisions and predicts complications like Graves' ophthalmopathy.

Accurate interpretation ensures optimal patient care.

Price of test:£180

The lowest price from the last 30 days: £180

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

Diagu's AI system represents a breakthrough in medical test analysis, employing state-of-the-art algorithms meticulously trained on a vast spectrum of authoritative medical literature and data. This system intricately analyses laboratory test results, extracting nuanced insights that might elude conventional methods. Our AI delves into complex interrelations between various health markers, offering a comprehensive understanding that supports accurate diagnosis and effective treatment planning. The foundation of our AI's analytical prowess lies in its extensive training, encompassing data from globally recognised medical journals, trusted healthcare databases, and breakthrough scientific studies. This ensures that every analysis is grounded in the latest and most comprehensive medical knowledge.

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At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

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