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Vitamin B6 (pyridoxine)

Vitamin B6 (pyridoxine)

The Vitamin B6 lab test is essential for assessing the body's levels of this crucial nutrient, which plays a vital role in numerous metabolic processes. Vitamin B6, or pyridoxine, is involved in neurotransmitter synthesis, amino acid metabolism, and blood sugar regulation, and is necessary for healthy nerve function and red blood cell production. The test primarily measures pyridoxal 5'-phosphate (PLP), the most active form of Vitamin B6, in plasma or serum. Accurate measurement is achieved through methods like liquid chromatography-tandem mass spectrometry (LC-MS/MS), which ensures precise detection of PLP levels. Proper specimen collection, including fasting and avoiding supplements before testing, is critical to prevent false results. The test results, expressed in micrograms per liter, help diagnose deficiencies and evaluate supplementation effectiveness. By providing insights into Vitamin B6 status, this test aids in managing health conditions linked to deficiencies, ensuring comprehensive patient care.

Price of test:£115

The lowest price from the last 30 days: £115

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

Vitamin B6, or pyridoxine, is vital for numerous bodily functions. Testing its levels helps diagnose deficiencies and assess supplementation effectiveness. Key points include:

- Biochemical Role: Acts as a coenzyme for over 160 enzymes, crucial for neurotransmitter synthesis, amino acid metabolism, and blood sugar regulation.
- Forms: Exists as pyridoxine, pyridoxal, pyridoxamine, and their phosphorylated derivatives, with PLP being the most active.
- Testing Methods: LC-MS/MS is commonly used for precise measurement.
- Specimen Handling: Requires careful collection and storage to prevent degradation.
- Clinical Relevance: Assists in diagnosing deficiencies and evaluating supplementation success.

Who Should Get Tested

Vitamin B6 testing is essential for individuals at risk of deficiency or with specific health conditions. Key groups include:

- Individuals with Symptoms: Those experiencing symptoms like fatigue, irritability, or nerve issues may need testing.
- Pregnant Women: To ensure adequate levels for fetal development.
- Elderly: Age-related absorption issues can lead to deficiencies.
- People with Chronic Conditions: Conditions like kidney disease or malabsorption syndromes may affect B6 levels.
- Individuals on Certain Medications: Some drugs can interfere with vitamin B6 metabolism.

Testing helps tailor supplementation and manage health effectively.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for vitamin B6 is essential for evaluating nutritional health. Here’s a brief guide:

- Reference Range: Plasma levels typically range from 3.4 µg/L to 65.2 µg/L.
- Deficiency: Levels below 3.4 µg/L indicate a deficiency.
- Marginal Levels: Between 3.4 µg/L and 5.1 µg/L.
- Adequate Levels: Above 5.1 µg/L.

These results help diagnose deficiencies and assess supplementation effectiveness. Proper specimen handling is crucial to ensure accuracy, avoiding false positives or negatives due to improper storage or fasting.

Price of test:£115

The lowest price from the last 30 days: £115

AI-Powered Insights and Expert Validation

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