AST (aspartate aminotransferase) is an enzyme used to assess liver and muscle health. When cells in the liver or muscles are damaged, AST is released into the bloodstream, raising its levels. Understanding the significance of high and low AST levels can provide valuable insights into various health conditions.
High AST Levels:
- Liver Damage:
- Elevated AST is a common indicator of liver conditions like hepatitis, cirrhosis, or liver cancer.
- Muscle Injury:
- Muscle trauma, overexertion, or diseases such as muscular dystrophy can increase AST levels.
- Heart Conditions:
- High AST levels can sometimes signal a recent heart attack or heart disease.
- Alcohol Abuse:
- Chronic alcohol use can lead to elevated AST, reflecting liver stress.
Low AST Levels:
- Nutritional Deficiencies:
- Low levels may be associated with a deficiency in vitamin B6, an important cofactor for AST production.
- Uncommon Significance:
- Low AST is generally not considered a clinical concern but may prompt a review of nutritional status.
Treatment Options:
- For High AST:
- Identify and treat the underlying cause (e.g., hepatitis, muscle damage, alcohol cessation).
- Regular monitoring and lifestyle changes may be necessary.
- For Low AST:
- Address nutritional deficiencies by supplementing vitamin B6, if needed.
Recommended Tests:
- Alanine Aminotransferase (ALT) Test
This test is often performed alongside the AST test to get a more comprehensive picture of liver function and help distinguish between liver and muscle damage.
Alanine Aminotransferase (ALT) Test - Creatine Kinase (CK) Test
To evaluate muscle health, the CK test can help determine if elevated AST levels are due to muscle damage.
Creatine Kinase (CK) Test
