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Diarrhoea - diagnosis, treatment, and recommended laboratory tests


Diarrhoea, a common yet potentially debilitating condition, manifests as the frequent passage of loose, watery stools, significantly affecting millions of people globally each year. It spans a spectrum from acute episodes, lasting a day or two, to chronic forms persisting for weeks on end. Both forms take a toll on an individual’s health, hydration levels, and overall quality of life.


At the heart of diarrhoea's onset lies a diverse array of causes. Infectious agents, including viruses, bacteria, or parasites, are primary culprits. Pathogens like Campylobacter spp and Mycoplasma genitalium thrive in contaminated environments, easily transmitted through food, water, or close interpersonal contact. Beyond infections, diarrhoea can also spring from food intolerance, reactions to medications, or underlying chronic conditions such as Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD).


The hallmark of diarrhoea is an increase in both the frequency and fluidity of bowel movements. This condition often comes hand-in-hand with abdominal discomfort, bloating, and, in more severe instances, warning signs of dehydration such as decreased urine output, dry mouth, and unusual tiredness. When coupled with fever, nausea, and vomiting, these symptoms can signal an underlying infection, necessitating swift medical intervention to mitigate potential health detriments.

When to See a Doctor

Medical advice becomes essential if diarrhoea extends beyond two days, manifests with excessive severity, or is accompanied by dehydration symptoms, high fever, or the presence of blood in the stool. These signals warrant immediate consultation to forestall complications, decipher underlying causes, and chart an effective treatment course.

Common Laboratory Tests

Deciphering the underlying cause of diarrhoea often necessitates a battery of laboratory tests, including:

The results of these tests are pivotal, guiding the clinician towards the appropriate treatment strategy, ranging from antibiotics for bacterial causes to supportive care aimed at symptom relief for viral instances.

Possible Underlying Conditions

Early diagnosis of diarrhoea not only offers immediate relief but can also reveal chronic conditions like Irritable Bowel Syndrome (IBS) or pinpoint infections necessitating targeted treatment. Such early detection and intervention significantly enhance patient outcomes.


Preventing diarrhoea largely revolves around stringent hygiene practices and food safety measures. Regular, thorough handwashing, ensuring the purity of drinking water, and steering clear of known dietary triggers can substantially lessen the risk of developing diarrhoea. Education on these fronts forms a cornerstone of public health initiatives aimed at reducing the incidence and impact of diarrhoea globally.


Unaddressed, diarrhoea can precipitate severe dehydration, nutrient malabsorption, and extended periods of ill health. The elderly and young children are particularly susceptible to these repercussions, underscoring the need for prompt diagnosis and treatment. Ensuring adequate hydration and pursuing specific treatments based on the diarrhoea's cause are critical steps to circumvent these potential complications.

Step Forward for Health!

Despite its prevalence, diarrhoea should never be disregarded or downplayed. Recognizing the symptoms early, understanding the scenarios that necessitate medical consultation, and undertaking recommended laboratory tests, including screenings for pathogens like Mycoplasma and Campylobacter, are crucial steps in addressing this condition.

Diarrhoea, in its essence, is both a symptom and a signal—a manifestation of the body's response to an irritant or infection that needs resolution. If you or a loved one is grappling with persistent or severe diarrhoea, it is imperative to seek medical advice. Doing so not only facilitates the exploration of potentially underlying conditions but also opens the pathway to effective treatment and swift recovery.

Diarrhoea remains a widespread concern, understanding its causes, preventative measures, and the importance of medical intervention for severe or persistent cases can greatly minimize its impact. Equip yourself with knowledge, and do not hesitate to seek out diagnostic options like the recommended tests for a comprehensive assessment. Prompt action can prevent complications, alleviate symptoms, and reveal any lurking conditions, guiding you towards a healthier, more comfortable life.


What are the primary causes of diarrhoea?

Diarrhoea can be triggered by a variety of factors, including infections from viruses, bacteria (such as Mycoplasma genitalium and Campylobacter spp), or parasites; reactions to food intolerances; adverse effects from medications; or underlying conditions like Irritable Bowel Syndrome (IBS).

When should you seek medical attention for diarrhoea?

It's critical to consult a healthcare professional if diarrhoea persists beyond two days, is excessively severe, accompanied by symptoms of dehydration, high fever, or the presence of blood in the stool. These conditions may signal a more serious underlying issue that requires immediate attention.

What are some common laboratory tests recommended for diagnosing diarrhoea?

Key diagnostic tests include the Mycoplasma genitalium PCR and Campylobacter spp tests to detect bacterial infections, a Full Blood Count (FBC) to check for signs of infection or inflammation, and the Faecal Occult Blood (FIT) test, which identifies hidden blood in the stool that could indicate gastrointestinal bleeding or infection.

How can diarrhoea be prevented?

Prevention hinges on maintaining excellent hygiene practices, such as regular handwashing, ensuring the purity of drinking water, and avoiding known dietary triggers. These measures can significantly reduce the risk of developing diarrhoea.

What are the complications of untreated diarrhoea?

If left unaddressed, diarrhoea can lead to severe dehydration, nutrient malabsorption, and prolonged periods of illness. Especially vulnerable are the elderly and young children, who may experience more severe repercussions from untreated diarrhoea.






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