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  4. Liver Function Test (LFT): What Are the Different Components?

Liver Function Test (LFT): What Are the Different Components?

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A Liver Function Test (LFT) is a blood test that assesses various enzymes, proteins, and substances produced by the liver to evaluate its health. The main components of an LFT include:

Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST): These enzymes indicate liver cell damage.

Alkaline Phosphatase (ALP): Measures bile duct issues or bone disease.

Bilirubin: Reflects liver’s ability to process waste.

Albumin and Total Protein: Show overall liver function.

LFTs help diagnose liver conditions like hepatitis, fatty liver disease, and cirrhosis.

Liver Function Tests (LFTs) consist of multiple measurements that provide a comprehensive picture of liver health. Each component of the LFT gives insight into different aspects of liver function:

  • Alanine Aminotransferase (ALT): ALT is an enzyme that helps convert proteins into energy for liver cells. High levels of ALT in the blood may indicate liver damage or inflammation, such as from hepatitis or fatty liver disease.
  • Aspartate Aminotransferase (AST): Like ALT, AST is another enzyme found in the liver. Elevated AST levels may suggest liver damage, although it can also be raised due to issues in other organs like the heart and muscles.
  • Alkaline Phosphatase (ALP): ALP is an enzyme related to bile ducts. High levels may indicate bile duct blockage, liver disease, or bone disorders. In children and pregnant women, ALP levels can naturally be elevated.
  • Bilirubin: Bilirubin is a waste product produced when red blood cells break down. High bilirubin levels can cause jaundice, indicating liver’s inability to filter waste properly. This could suggest liver disease or bile duct problems.
  • Albumin and Total Protein: Albumin is the main protein produced by the liver, crucial for maintaining fluid balance in the blood. Low albumin levels can indicate liver disease or poor protein intake.

By evaluating these components, healthcare providers can identify liver diseases early, monitor existing conditions, and assess overall liver function.

Recommended Tests:

  1. Alanine Aminotransferase (ALT)
    Measures the enzyme linked to liver damage, often elevated in liver disease.
    Alanine Aminotransferase (ALT)
  2. Gamma-Glutamyl Transferase (GGT)
    This enzyme helps detect bile duct problems and alcohol-related liver disease.
    Gamma-Glutamyl Transferase (GGT)

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